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Dietary tryptophan metabolite released by intratumoral Lactobacillus reuteri facilitates immune checkpoint inhibitor treatment.
Bender, Mackenzie J; McPherson, Alex C; Phelps, Catherine M; Pandey, Surya P; Laughlin, Colin R; Shapira, Jake H; Medina Sanchez, Luzmariel; Rana, Mohit; Richie, Tanner G; Mims, Tahliyah S; Gocher-Demske, Angela M; Cervantes-Barragan, Luisa; Mullett, Steven J; Gelhaus, Stacy L; Bruno, Tullia C; Cannon, Nikki; McCulloch, John A; Vignali, Dario A A; Hinterleitner, Reinhard; Joglekar, Alok V; Pierre, Joseph F; Lee, Sonny T M; Davar, Diwakar; Zarour, Hassane M; Meisel, Marlies.
Afiliación
  • Bender MJ; Department of Immunology, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA.
  • McPherson AC; Department of Immunology, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA; Department of Infectious Diseases and Microbiology, University of Pittsburgh School of Public Health, Pittsburgh, PA, USA.
  • Phelps CM; Department of Immunology, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA; Graduate Program of Microbiology and Immunology, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA.
  • Pandey SP; Department of Immunology, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA.
  • Laughlin CR; Department of Immunology, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA.
  • Shapira JH; Department of Immunology, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA.
  • Medina Sanchez L; Department of Immunology, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA; Graduate Program of Microbiology and Immunology, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA.
  • Rana M; Department of Immunology, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA.
  • Richie TG; Division of Biology, Kansas State University, Manhattan, KS, USA.
  • Mims TS; Department of Nutritional Sciences, University of Wisconsin-Madison, Madison, WI, USA.
  • Gocher-Demske AM; Department of Immunology, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA; Tumor Microenvironment Center, UPMC Hillman Cancer Center, Pittsburgh, PA, USA.
  • Cervantes-Barragan L; Department of Microbiology and Immunology, Emory University, Atlanta, GA, USA.
  • Mullett SJ; Department of Pharmacology and Chemical Biology, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA; Health Sciences Mass Spectrometry Core, University of Pittsburgh, Pittsburgh, PA, USA.
  • Gelhaus SL; Department of Pharmacology and Chemical Biology, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA; Health Sciences Mass Spectrometry Core, University of Pittsburgh, Pittsburgh, PA, USA.
  • Bruno TC; Department of Immunology, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA; Tumor Microenvironment Center, UPMC Hillman Cancer Center, Pittsburgh, PA, USA; Cancer Immunology and Immunotherapy Program, UPMC Hillman Cancer Center, Pittsburgh, PA, USA.
  • Cannon N; Genetics and Microbiome Core, Laboratory of Integrative Cancer Immunology, Center for Cancer Research, National Cancer Institute, Bethesda, MD, USA.
  • McCulloch JA; Genetics and Microbiome Core, Laboratory of Integrative Cancer Immunology, Center for Cancer Research, National Cancer Institute, Bethesda, MD, USA.
  • Vignali DAA; Department of Immunology, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA; Tumor Microenvironment Center, UPMC Hillman Cancer Center, Pittsburgh, PA, USA; Cancer Immunology and Immunotherapy Program, UPMC Hillman Cancer Center, Pittsburgh, PA, USA.
  • Hinterleitner R; Department of Immunology, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA; Cancer Immunology and Immunotherapy Program, UPMC Hillman Cancer Center, Pittsburgh, PA, USA.
  • Joglekar AV; Department of Immunology, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA; Cancer Immunology and Immunotherapy Program, UPMC Hillman Cancer Center, Pittsburgh, PA, USA; Center for Systems Immunology, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA.
  • Pierre JF; Department of Nutritional Sciences, University of Wisconsin-Madison, Madison, WI, USA.
  • Lee STM; Division of Biology, Kansas State University, Manhattan, KS, USA.
  • Davar D; Cancer Immunology and Immunotherapy Program, UPMC Hillman Cancer Center, Pittsburgh, PA, USA; Department of Medicine and UPMC Hillman Cancer Center, University of Pittsburgh, Pittsburgh, PA, USA.
  • Zarour HM; Department of Immunology, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA; Cancer Immunology and Immunotherapy Program, UPMC Hillman Cancer Center, Pittsburgh, PA, USA; Department of Medicine and UPMC Hillman Cancer Center, University of Pittsburgh, Pittsburgh, PA, USA.
  • Meisel M; Department of Immunology, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA; Cancer Immunology and Immunotherapy Program, UPMC Hillman Cancer Center, Pittsburgh, PA, USA. Electronic address: marlies@pitt.edu.
Cell ; 186(9): 1846-1862.e26, 2023 04 27.
Article en En | MEDLINE | ID: mdl-37028428
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Texto completo: 1 Base de datos: MEDLINE Asunto principal: Limosilactobacillus reuteri / Microambiente Tumoral / Melanoma Idioma: En Revista: Cell Año: 2023 Tipo del documento: Article
Texto completo
Imprimir
XML
PubMed Links
Buscar en Google

Texto completo: 1 Base de datos: MEDLINE Asunto principal: Limosilactobacillus reuteri / Microambiente Tumoral / Melanoma Idioma: En Revista: Cell Año: 2023 Tipo del documento: Article