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Core polymer optimization of ternary siRNA nanoparticles enhances in vivo safety, pharmacokinetics, and tumor gene silencing.
Patel, Shrusti S; Hoogenboezem, Ella N; Yu, Fang; DeJulius, Carlisle R; Fletcher, R Brock; Sorets, Alex G; Cherry, Fiona K; Lo, Justin H; Bezold, Mariah G; Francini, Nora; d'Arcy, Richard; Brasuell, Jordan E; Cook, Rebecca S; Duvall, Craig L.
Afiliación
  • Patel SS; Department of Biomedical Engineering, Vanderbilt University, Nashville, TN, USA.
  • Hoogenboezem EN; Department of Biomedical Engineering, Vanderbilt University, Nashville, TN, USA.
  • Yu F; Department of Biomedical Engineering, Vanderbilt University, Nashville, TN, USA.
  • DeJulius CR; Department of Biomedical Engineering, Vanderbilt University, Nashville, TN, USA.
  • Fletcher RB; Department of Biomedical Engineering, Vanderbilt University, Nashville, TN, USA.
  • Sorets AG; Department of Biomedical Engineering, Vanderbilt University, Nashville, TN, USA.
  • Cherry FK; Department of Biomedical Engineering, Vanderbilt University, Nashville, TN, USA.
  • Lo JH; Department of Biomedical Engineering, Vanderbilt University, Nashville, TN, USA; Division of Hematology/Oncology, Department of Internal Medicine, Vanderbilt University Medical Center, Nashville, TN, USA.
  • Bezold MG; Department of Biomedical Engineering, Vanderbilt University, Nashville, TN, USA.
  • Francini N; Department of Biomedical Engineering, Vanderbilt University, Nashville, TN, USA.
  • d'Arcy R; Department of Biomedical Engineering, Vanderbilt University, Nashville, TN, USA.
  • Brasuell JE; Department of Biomedical Engineering, Vanderbilt University, Nashville, TN, USA.
  • Cook RS; Department of Biomedical Engineering, Vanderbilt University, Nashville, TN, USA.
  • Duvall CL; Department of Biomedical Engineering, Vanderbilt University, Nashville, TN, USA. Electronic address: craig.duvall@vanderbilt.edu.
Biomaterials ; 297: 122098, 2023 06.
Article en En | MEDLINE | ID: mdl-37031547
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Texto completo: 1 Base de datos: MEDLINE Asunto principal: Polímeros / Nanopartículas Idioma: En Revista: Biomaterials Año: 2023 Tipo del documento: Article
Texto completo
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PubMed Links
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Texto completo: 1 Base de datos: MEDLINE Asunto principal: Polímeros / Nanopartículas Idioma: En Revista: Biomaterials Año: 2023 Tipo del documento: Article