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α-Synuclein Preformed Fibrils Bind to ß-Neurexins and Impair ß-Neurexin-Mediated Presynaptic Organization.
Feller, Benjamin; Fallon, Aurélie; Luo, Wen; Nguyen, Phuong Trang; Shlaifer, Irina; Lee, Alfred Kihoon; Chofflet, Nicolas; Yi, Nayoung; Khaled, Husam; Karkout, Samer; Bourgault, Steve; Durcan, Thomas M; Takahashi, Hideto.
Afiliación
  • Feller B; Synapse Development and Plasticity Research Unit, Institut de Recherches Cliniques de Montréal, Montreal, QC H2W 1R7, Canada.
  • Fallon A; Department of Medicine, Université de Montréal, Montreal, QC H3T 1J4, Canada.
  • Luo W; Synapse Development and Plasticity Research Unit, Institut de Recherches Cliniques de Montréal, Montreal, QC H2W 1R7, Canada.
  • Nguyen PT; Department of Medicine, Université de Montréal, Montreal, QC H3T 1J4, Canada.
  • Shlaifer I; The Neuro's Early Drug Discovery Unit (EDDU), Department of Neurology and Neurosurgery, Montreal Neurological Institute-Hospital, McGill University, Montreal, QC H3A 2B4, Canada.
  • Lee AK; Department of Chemistry, Quebec Network for Research on Protein Function, Engineering and Applications, PROTEO, Université du Québec à Montréal, Montreal, QC H3C 3P8, Canada.
  • Chofflet N; The Neuro's Early Drug Discovery Unit (EDDU), Department of Neurology and Neurosurgery, Montreal Neurological Institute-Hospital, McGill University, Montreal, QC H3A 2B4, Canada.
  • Yi N; Synapse Development and Plasticity Research Unit, Institut de Recherches Cliniques de Montréal, Montreal, QC H2W 1R7, Canada.
  • Khaled H; Integrated Program in Neuroscience, McGill University, Montreal, QC H3A 2B2, Canada.
  • Karkout S; Synapse Development and Plasticity Research Unit, Institut de Recherches Cliniques de Montréal, Montreal, QC H2W 1R7, Canada.
  • Bourgault S; Integrated Program in Neuroscience, McGill University, Montreal, QC H3A 2B2, Canada.
  • Durcan TM; Synapse Development and Plasticity Research Unit, Institut de Recherches Cliniques de Montréal, Montreal, QC H2W 1R7, Canada.
  • Takahashi H; Department of Medicine, Université de Montréal, Montreal, QC H3T 1J4, Canada.
Cells ; 12(7)2023 04 04.
Article en En | MEDLINE | ID: mdl-37048156
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Texto completo: 1 Base de datos: MEDLINE Asunto principal: Enfermedad de Parkinson / Sinucleinopatías Idioma: En Revista: Cells Año: 2023 Tipo del documento: Article
Texto completo
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PubMed Links
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Texto completo: 1 Base de datos: MEDLINE Asunto principal: Enfermedad de Parkinson / Sinucleinopatías Idioma: En Revista: Cells Año: 2023 Tipo del documento: Article