Comprehensive single-cell transcriptomic and proteomic analysis reveals NK cell exhaustion and unique tumor cell evolutionary trajectory in non-keratinizing nasopharyngeal carcinoma.

Chen, Cuimin; Wang, Chun; Pang, Ruifang; Liu, Huanyu; Yin, Weihua; Chen, Jiakang; Tao, Lili

Chen, Cuimin; Wang, Chun; Pang, Ruifang; Liu, Huanyu; Yin, Weihua; Chen, Jiakang; Tao, Lili.

Afiliación

Chen C; Department of Pathology, Peking University Shenzhen Hospital, Shenzhen, China.
Wang C; Department of Pathology, Peking University Shenzhen Hospital, Shenzhen, China.
Pang R; Department of Precision Research Institute, Peking University Shenzhen Hospital, Shenzhen, China.
Liu H; Department of Pathology, Peking University Shenzhen Hospital, Shenzhen, China.
Yin W; Department of Pathology, Peking University Shenzhen Hospital, Shenzhen, China.
Chen J; Department of Pathology, Peking University Shenzhen Hospital, Shenzhen, China. 2228778160@qq.com.
Tao L; Department of Pathology, Peking University Shenzhen Hospital, Shenzhen, China. 651055473@qq.com.

J Transl Med ; 21(1): 278, 2023 04 25.

Article en En | MEDLINE | ID: mdl-37098551

Asunto(s)

Infecciones por Virus de Epstein-Barr; Neoplasias de Cabeza y Cuello; Neoplasias Nasofaríngeas; Humanos; Carcinoma Nasofaríngeo/genética; Infecciones por Virus de Epstein-Barr/complicaciones; Neoplasias Nasofaríngeas/genética; Transcriptoma/genética; Proteómica; Herpesvirus Humano 4/fisiología; Células Asesinas Naturales/metabolismo; Carcinoma de Células Escamosas de Cabeza y Cuello

Palabras clave

EBV; Evolutionary trajectory; NK cell exhaustion; NK-NPC; Proteomics; single-cell RNA sequencing

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Texto completo: 1 Base de datos: MEDLINE Asunto principal: Neoplasias Nasofaríngeas / Infecciones por Virus de Epstein-Barr / Neoplasias de Cabeza y Cuello Tipo de estudio: Prognostic_studies Idioma: En Revista: J Transl Med Año: 2023 Tipo del documento: Article

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