Modulation of DNA-protein Interactions by Proximal Genetic Elements as Uncovered by Interpretable Deep Learning.

Kalakoti, Yogesh; Peter, Swathik Clarancia; Gawande, Swaraj; Sundar, Durai

Kalakoti, Yogesh; Peter, Swathik Clarancia; Gawande, Swaraj; Sundar, Durai.

Afiliación

Kalakoti Y; Department of Biochemical Engineering & Biotechnology, Indian Institute of Technology (IIT) Delhi, New Delhi 110016, India. Electronic address: yogesh.kalakoti@dbeb.iitd.ac.in.
Peter SC; Department of Biochemical Engineering & Biotechnology, Indian Institute of Technology (IIT) Delhi, New Delhi 110016, India; Regional Centre for Biotechnology (RCB), Faridabad, Haryana 121001, India. Electronic address: pswathik.clarancia@rcb.res.in.
Gawande S; Department of Computer Science and Engineering, Indian Institute of Technology (IIT) Delhi, New Delhi 110016, India. Electronic address: cs1190406@cse.iitd.ac.in.
Sundar D; Department of Biochemical Engineering & Biotechnology, Indian Institute of Technology (IIT) Delhi, New Delhi 110016, India; Yardi School of Artificial Intelligence, Indian Institute of Technology (IIT) Delhi, New Delhi 110016, India. Electronic address: sundar@dbeb.iitd.ac.in.

J Mol Biol ; 435(13): 168121, 2023 07 01.

Article en En | MEDLINE | ID: mdl-37100167

Asunto(s)

ADN; Aprendizaje Profundo; Factores de Transcripción; Sitios de Unión/genética; ADN/metabolismo; Unión Proteica; Factores de Transcripción/metabolismo

Palabras clave

DNA binding; attention; transcription factor; transfer learning

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Texto completo: 1 Base de datos: MEDLINE Asunto principal: Factores de Transcripción / ADN / Aprendizaje Profundo Tipo de estudio: Prognostic_studies Idioma: En Revista: J Mol Biol Año: 2023 Tipo del documento: Article

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