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Discovery of diarylpyrimidine derivatives bearing piperazine sulfonyl as potent HIV-1 nonnucleoside reverse transcriptase inhibitors.
Jiang, Xiangyi; Huang, Boshi; Rumrill, Shawn; Pople, David; Zalloum, Waleed A; Kang, Dongwei; Zhao, Fabao; Ji, Xiangkai; Gao, Zhen; Hu, Lide; Wang, Zhao; Xie, Minghui; De Clercq, Erik; Ruiz, Francesc X; Arnold, Eddy; Pannecouque, Christophe; Liu, Xinyong; Zhan, Peng.
Afiliación
  • Jiang X; Department of Medicinal Chemistry, Key Laboratory of Chemical Biology (Ministry of Education), School of Pharmaceutical Sciences, Cheeloo College of Medicine, Shandong University, 44 West Culture Road, Jinan, 250012, Shandong, PR China.
  • Huang B; Department of Medicinal Chemistry, Key Laboratory of Chemical Biology (Ministry of Education), School of Pharmaceutical Sciences, Cheeloo College of Medicine, Shandong University, 44 West Culture Road, Jinan, 250012, Shandong, PR China.
  • Rumrill S; Center for Advanced Biotechnology and Medicine, Rutgers University, Piscataway, NJ, 08854, USA.
  • Pople D; Department of Chemistry and Chemical Biology, Rutgers University, Piscataway, NJ, 08854, USA.
  • Zalloum WA; Center for Advanced Biotechnology and Medicine, Rutgers University, Piscataway, NJ, 08854, USA.
  • Kang D; Department of Chemistry and Chemical Biology, Rutgers University, Piscataway, NJ, 08854, USA.
  • Zhao F; Department of Pharmacy, Faculty of Health Science, American University of Madaba, P.O Box 2882, Amman, 11821, Jordan.
  • Ji X; Department of Medicinal Chemistry, Key Laboratory of Chemical Biology (Ministry of Education), School of Pharmaceutical Sciences, Cheeloo College of Medicine, Shandong University, 44 West Culture Road, Jinan, 250012, Shandong, PR China.
  • Gao Z; China-Belgium Collaborative Research Center for Innovative Antiviral Drugs of Shandong Province, 44 West Culture Road, Jinan, 250012, Shandong, PR China.
  • Hu L; Department of Medicinal Chemistry, Key Laboratory of Chemical Biology (Ministry of Education), School of Pharmaceutical Sciences, Cheeloo College of Medicine, Shandong University, 44 West Culture Road, Jinan, 250012, Shandong, PR China.
  • Wang Z; Department of Medicinal Chemistry, Key Laboratory of Chemical Biology (Ministry of Education), School of Pharmaceutical Sciences, Cheeloo College of Medicine, Shandong University, 44 West Culture Road, Jinan, 250012, Shandong, PR China.
  • Xie M; Department of Medicinal Chemistry, Key Laboratory of Chemical Biology (Ministry of Education), School of Pharmaceutical Sciences, Cheeloo College of Medicine, Shandong University, 44 West Culture Road, Jinan, 250012, Shandong, PR China.
  • De Clercq E; Department of Medicinal Chemistry, Key Laboratory of Chemical Biology (Ministry of Education), School of Pharmaceutical Sciences, Cheeloo College of Medicine, Shandong University, 44 West Culture Road, Jinan, 250012, Shandong, PR China.
  • Ruiz FX; Department of Medicinal Chemistry, Key Laboratory of Chemical Biology (Ministry of Education), School of Pharmaceutical Sciences, Cheeloo College of Medicine, Shandong University, 44 West Culture Road, Jinan, 250012, Shandong, PR China.
  • Arnold E; Department of Medicinal Chemistry, Key Laboratory of Chemical Biology (Ministry of Education), School of Pharmaceutical Sciences, Cheeloo College of Medicine, Shandong University, 44 West Culture Road, Jinan, 250012, Shandong, PR China.
  • Pannecouque C; Rega Institute for Medical Research, Laboratory of Virology and Chemotherapy, K.U.Leuven, Herestraat 49 Postbus 1043 (09.A097), B-3000, Leuven, Belgium.
  • Liu X; Center for Advanced Biotechnology and Medicine, Rutgers University, Piscataway, NJ, 08854, USA. fr193@cabm.rutgers.edu.
  • Zhan P; Department of Chemistry and Chemical Biology, Rutgers University, Piscataway, NJ, 08854, USA. fr193@cabm.rutgers.edu.
Commun Chem ; 6(1): 83, 2023 Apr 29.
Article en En | MEDLINE | ID: mdl-37120482
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Texto completo: 1 Base de datos: MEDLINE Idioma: En Revista: Commun Chem Año: 2023 Tipo del documento: Article
Texto completo
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Texto completo: 1 Base de datos: MEDLINE Idioma: En Revista: Commun Chem Año: 2023 Tipo del documento: Article