Neurophysiological and psychosocial mechanisms of fibromyalgia: A comprehensive review and call for an integrative model.
Neurosci Biobehav Rev
; 151: 105235, 2023 08.
Article
en En
| MEDLINE
| ID: mdl-37207842
ABSTRACT
Research into the neurobiological and psychosocial mechanisms involved in fibromyalgia has progressed remarkably in recent years. Despite this, current accounts of fibromyalgia fail to capture the complex, dynamic, and mutual crosstalk between neurophysiological and psychosocial domains. We conducted a comprehensive review of the existing literature in order to a) synthesize current knowledge on fibromyalgia; b) explore and highlight multi-level links and pathways between different systems; and c) build bridges connecting disparate perspectives. An extensive panel of international experts in neurophysiological and psychosocial aspects of fibromyalgia discussed the collected evidence and progressively refined and conceptualized its interpretation. This work constitutes an essential step towards the development of a model capable of integrating the main factors implicated in fibromyalgia into a single, unified construct which appears indispensable to foster the understanding, assessment, and intervention for fibromyalgia.
Palabras clave
Texto completo:
1
Base de datos:
MEDLINE
Asunto principal:
Fibromialgia
/
Modelos Biopsicosociales
Tipo de estudio:
Prognostic_studies
Idioma:
En
Revista:
Neurosci Biobehav Rev
Año:
2023
Tipo del documento:
Article