Acquired Von Willebrand Factor Deficiency at Patient-Prosthesis Mismatch after AVR Procedure-A Narrative Review.
Medicina (Kaunas)
; 59(5)2023 May 16.
Article
en En
| MEDLINE
| ID: mdl-37241186
ABSTRACT
Acquired von Willebrand factor deficiency has been described in patients with aortic valve stenosis due to high shear forces developed during passage through the narrowed valve orifice, which determines structural changes in this molecule. Similar flow conditions are present in patients with an aortic prosthesis that presents a patient-prosthesis mismatch. Patient-prosthesis mismatch is described by the smaller effective orifice area of the prosthesis than the native valve, which would probably determine similar changes in the molecules of the von Willebrand factor, leading to acquiring von Willebrand deficiency.
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Base de datos:
MEDLINE
Asunto principal:
Estenosis de la Válvula Aórtica
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Enfermedades de von Willebrand
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Prótesis Valvulares Cardíacas
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Implantación de Prótesis de Válvulas Cardíacas
Idioma:
En
Revista:
Medicina (Kaunas)
Asunto de la revista:
MEDICINA
Año:
2023
Tipo del documento:
Article