Development of Novel Small-Molecule Activators of Pyruvate Kinase Muscle Isozyme 2, PKM2, to Reduce Photoreceptor Apoptosis.

Wubben, Thomas J; Chaudhury, Sraboni; Watch, Brennan T; Stuckey, Jeanne A; Weh, Eric; Fernando, Roshini; Goswami, Moloy; Pawar, Mercy; Rech, Jason C; Besirli, Cagri G

Wubben, Thomas J; Chaudhury, Sraboni; Watch, Brennan T; Stuckey, Jeanne A; Weh, Eric; Fernando, Roshini; Goswami, Moloy; Pawar, Mercy; Rech, Jason C; Besirli, Cagri G.

Afiliación

Wubben TJ; Department of Ophthalmology and Visual Sciences, Kellogg Eye Center, University of Michigan, Ann Arbor, MI 48105, USA.
Chaudhury S; Department of Ophthalmology and Visual Sciences, Kellogg Eye Center, University of Michigan, Ann Arbor, MI 48105, USA.
Watch BT; Department of Internal Medicine, Hematology and Oncology, Michigan Center for Therapeutic Innovation, University of Michigan, Ann Arbor, MI 48109, USA.
Stuckey JA; Departments of Biological Chemistry and Biophysics, Center for Structural Biology, University of Michigan, Ann Arbor, MI 48109, USA.
Weh E; Department of Ophthalmology and Visual Sciences, Kellogg Eye Center, University of Michigan, Ann Arbor, MI 48105, USA.
Fernando R; Department of Ophthalmology and Visual Sciences, Kellogg Eye Center, University of Michigan, Ann Arbor, MI 48105, USA.
Goswami M; Department of Ophthalmology and Visual Sciences, Kellogg Eye Center, University of Michigan, Ann Arbor, MI 48105, USA.
Pawar M; Department of Ophthalmology and Visual Sciences, Kellogg Eye Center, University of Michigan, Ann Arbor, MI 48105, USA.
Rech JC; Department of Internal Medicine, Hematology and Oncology, Michigan Center for Therapeutic Innovation, University of Michigan, Ann Arbor, MI 48109, USA.
Besirli CG; Department of Ophthalmology and Visual Sciences, Kellogg Eye Center, University of Michigan, Ann Arbor, MI 48105, USA.