Differential toxicity and localization of arginine-rich <i>C9ORF72</i> dipeptide repeat proteins depend on de-clustering of positive charges.

Miyagi, Tamami; Ueda, Koji; Sugimoto, Masahiro; Yagi, Takuya; Ito, Daisuke; Yamazaki, Rio; Narumi, Satoshi; Hayamizu, Yuhei; Uji-I, Hiroshi; Kuroda, Masahiko; Kanekura, Kohsuke

Differential toxicity and localization of arginine-rich C9ORF72 dipeptide repeat proteins depend on de-clustering of positive charges.

Miyagi, Tamami; Ueda, Koji; Sugimoto, Masahiro; Yagi, Takuya; Ito, Daisuke; Yamazaki, Rio; Narumi, Satoshi; Hayamizu, Yuhei; Uji-I, Hiroshi; Kuroda, Masahiko; Kanekura, Kohsuke.

Afiliación

Miyagi T; Department of Molecular Pathology, Tokyo Medical University, 6-1-1 Shinjuku, Shinjuku-ku, Tokyo 160-8402, Japan.
Ueda K; Department of Pharmacology, Tokyo Medical University, 6-1-1 Shinjuku, Shinjuku-ku, Tokyo 160-8402, Japan.
Sugimoto M; Cancer Proteomics Group, Cancer Precision Medicine Center, Japanese Foundation for Cancer Research, 3-8-31 Ariake, Koto-ku, Tokyo 135-8550, Japan.
Yagi T; Research and Development Center for Minimally Invasive Therapies, Tokyo Medical University, 6-1-1 Shinjuku, Shinjuku-ku, Tokyo 160-8402, Japan.
Ito D; Institute for Advanced Biosciences, KEIO University, 246-2 Mizukami, Kakuganji, Tsuruoka, Yamagata 997-0052, Japan.
Yamazaki R; Department of Neurology, KEIO University School of Medicine, 35 Shinanomachi, Shinjuku-ku, Tokyo 160-8582, Japan.
Narumi S; Department of Physiology, KEIO University School of Medicine, 35 Shinanomachi, Shinjuku-ku, Tokyo 160-8582, Japan.
Hayamizu Y; Department of Molecular Pathology, Tokyo Medical University, 6-1-1 Shinjuku, Shinjuku-ku, Tokyo 160-8402, Japan.
Uji-I H; Department of Pharmacology, Tokyo Medical University, 6-1-1 Shinjuku, Shinjuku-ku, Tokyo 160-8402, Japan.
Kuroda M; Department of Molecular Endocrinology, National Research Institute for Child Health and Development, 2-10-1 Okura, Setagaya-ku, Tokyo 157-8535, Japan.
Kanekura K; Department of Materials Science and Engineering, School of Materials and Chemical Technology, Tokyo Institute of Technology, 2-12-1, Ookayama, Meguro-ku, Tokyo 152-8550, Japan.