Discovery of 4-aminoindole carboxamide derivatives to curtail alpha-synuclein and tau isoform 2N4R oligomer formation.

Ramirez, Eduardo; Min, Sehong; Ganegamage, Susantha K; Shimanaka, Kazuma; Sosa, Magaly Guzman; Dettmer, Ulf; Rochet, Jean-Christophe; Fortin, Jessica S.

Afiliación

Ramirez E; Department of Basic Medical Sciences, College of Veterinary Medicine, Purdue University.
Min S; Department of Medicinal Chemistry and Molecular Pharmacology, College of Pharmacy, Purdue University.
Ganegamage SK; Department of Basic Medical Sciences, College of Veterinary Medicine, Purdue University.
Shimanaka K; Ann Romney Center for Neurologic Diseases, Department of Neurology, Brigham and Women's Hospital and Harvard Medical School, Boston, MA 02115, United States.
Sosa MG; Department of Medicinal Chemistry and Molecular Pharmacology, College of Pharmacy, Purdue University.
Dettmer U; Ann Romney Center for Neurologic Diseases, Department of Neurology, Brigham and Women's Hospital and Harvard Medical School, Boston, MA 02115, United States.
Rochet JC; Department of Medicinal Chemistry and Molecular Pharmacology, College of Pharmacy, Purdue University.
Fortin JS; Department of Basic Medical Sciences, College of Veterinary Medicine, Purdue University.

Results Chem ; 52023 Jan.

Article en En | MEDLINE | ID: mdl-37346091