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Cooperative sensing of mitochondrial DNA by ZBP1 and cGAS promotes cardiotoxicity.
Lei, Yuanjiu; VanPortfliet, Jordyn J; Chen, Yi-Fan; Bryant, Joshua D; Li, Ying; Fails, Danielle; Torres-Odio, Sylvia; Ragan, Katherine B; Deng, Jingti; Mohan, Armaan; Wang, Bing; Brahms, Olivia N; Yates, Shawn D; Spencer, Michael; Tong, Carl W; Bosenberg, Marcus W; West, Laura Ciaccia; Shadel, Gerald S; Shutt, Timothy E; Upton, Jason W; Li, Pingwei; West, A Phillip.
Afiliación
  • Lei Y; Department of Microbial Pathogenesis and Immunology, School of Medicine, Texas A&M University, Bryan, TX 77807, USA.
  • VanPortfliet JJ; Department of Microbial Pathogenesis and Immunology, School of Medicine, Texas A&M University, Bryan, TX 77807, USA.
  • Chen YF; Department of Microbial Pathogenesis and Immunology, School of Medicine, Texas A&M University, Bryan, TX 77807, USA.
  • Bryant JD; Department of Microbial Pathogenesis and Immunology, School of Medicine, Texas A&M University, Bryan, TX 77807, USA.
  • Li Y; Department of Biochemistry and Biophysics, Texas A&M University, College Station, TX 77843, USA.
  • Fails D; Fortis Life Sciences, Montgomery, TX 77356, USA.
  • Torres-Odio S; Department of Microbial Pathogenesis and Immunology, School of Medicine, Texas A&M University, Bryan, TX 77807, USA.
  • Ragan KB; Department of Molecular Biosciences, University of Texas at Austin, Austin, TX 78712, USA.
  • Deng J; Departments of Medical Genetics and Biochemistry & Molecular Biology, Cumming School of Medicine, University of Calgary, Calgary, AB T2N 1N4, Canada.
  • Mohan A; Departments of Medical Genetics and Biochemistry & Molecular Biology, Cumming School of Medicine, University of Calgary, Calgary, AB T2N 1N4, Canada.
  • Wang B; Department of Biochemistry and Biophysics, Texas A&M University, College Station, TX 77843, USA.
  • Brahms ON; Department of Biological Sciences, Auburn University, Auburn, AL 36849, USA.
  • Yates SD; Department of Biological Sciences, Auburn University, Auburn, AL 36849, USA.
  • Spencer M; Fortis Life Sciences, Montgomery, TX 77356, USA.
  • Tong CW; Department of Medical Physiology, School of Medicine, Texas A&M University, Bryan, TX 77807, USA.
  • Bosenberg MW; Departments of Pathology, Dermatology, and Immunobiology, Yale School of Medicine, New Haven, CT 06520, USA.
  • West LC; Department of Microbial Pathogenesis and Immunology, School of Medicine, Texas A&M University, Bryan, TX 77807, USA.
  • Shadel GS; Salk Institute for Biological Studies, La Jolla, CA 92037, USA.
  • Shutt TE; Departments of Medical Genetics and Biochemistry & Molecular Biology, Cumming School of Medicine, University of Calgary, Calgary, AB T2N 1N4, Canada.
  • Upton JW; Department of Biological Sciences, Auburn University, Auburn, AL 36849, USA.
  • Li P; Department of Biochemistry and Biophysics, Texas A&M University, College Station, TX 77843, USA.
  • West AP; Department of Microbial Pathogenesis and Immunology, School of Medicine, Texas A&M University, Bryan, TX 77807, USA. Electronic address: awest@tamu.edu.
Cell ; 186(14): 3013-3032.e22, 2023 07 06.
Article en En | MEDLINE | ID: mdl-37352855
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Texto completo: 1 Base de datos: MEDLINE Asunto principal: ADN Mitocondrial / Cardiotoxicidad Idioma: En Revista: Cell Año: 2023 Tipo del documento: Article
Texto completo
Imprimir
XML
PubMed Links
Buscar en Google

Texto completo: 1 Base de datos: MEDLINE Asunto principal: ADN Mitocondrial / Cardiotoxicidad Idioma: En Revista: Cell Año: 2023 Tipo del documento: Article