Synthesis of a Complex and Highly Potent PCSK9 Inhibitor.

Kuethe, Jeffrey T; Lee, Joshua; Thaisrivongs, David; Yasuda, Nobuyoshi; Pollack, Scott R; Leone, Joseph; DaSilva, Jimmy; Biba, Mirlinda; Tsay, Fuh-Rong; Regalado, Erik L; Qi, Ji; Li, Hongming; Poggetto, Guilherme Dal; Cohen, Ryan

Kuethe, Jeffrey T; Lee, Joshua; Thaisrivongs, David; Yasuda, Nobuyoshi; Pollack, Scott R; Leone, Joseph; DaSilva, Jimmy; Biba, Mirlinda; Tsay, Fuh-Rong; Regalado, Erik L; Qi, Ji; Li, Hongming; Poggetto, Guilherme Dal; Cohen, Ryan.

Afiliación

Kuethe JT; Department of Process Research and Development, Merck & Co., Inc., Rahway, New Jersey 07065, United States.
Lee J; Department of Process Research and Development, Merck & Co., Inc., Rahway, New Jersey 07065, United States.
Thaisrivongs D; Department of Process Research and Development, Merck & Co., Inc., Rahway, New Jersey 07065, United States.
Yasuda N; Department of Process Research and Development, Merck & Co., Inc., Rahway, New Jersey 07065, United States.
Pollack SR; Department of Process Research and Development, Merck & Co., Inc., Rahway, New Jersey 07065, United States.
Leone J; Department of Process Research and Development, Merck & Co., Inc., Rahway, New Jersey 07065, United States.
DaSilva J; Department of Process Research and Development, Merck & Co., Inc., Rahway, New Jersey 07065, United States.
Biba M; Department of Process Research and Development, Merck & Co., Inc., Rahway, New Jersey 07065, United States.
Tsay FR; Department of Process Research and Development, Merck & Co., Inc., Rahway, New Jersey 07065, United States.
Regalado EL; Department of Process Research and Development, Merck & Co., Inc., Rahway, New Jersey 07065, United States.
Qi J; Department of Process Research and Development, Merck & Co., Inc., Rahway, New Jersey 07065, United States.
Li H; Department of Process Research and Development, Merck & Co., Inc., Rahway, New Jersey 07065, United States.
Poggetto GD; Department of Process Research and Development, Merck & Co., Inc., Rahway, New Jersey 07065, United States.
Cohen R; Department of Process Research and Development, Merck & Co., Inc., Rahway, New Jersey 07065, United States.

Org Lett ; 25(27): 5001-5005, 2023 07 14.

Article en En | MEDLINE | ID: mdl-37382389

Asunto(s)

Proproteína Convertasa 9

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Texto completo: 1 Base de datos: MEDLINE Asunto principal: Proproteína Convertasa 9 Idioma: En Revista: Org Lett Asunto de la revista: BIOQUIMICA Año: 2023 Tipo del documento: Article

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