Selective inhibition of neurogenic, but not agonist-induced contractions by phospholipase A<sub>2</sub> inhibitors points to presynaptic phospholipase A<sub>2</sub> functions in contractile neurotransmission to human prostate smooth muscle.

Hu, Sheng; Huang, Ru; Keller, Patrick; Götz, Melanie; Tamalunas, Alexander; Weinhold, Philipp; Waidelich, Raphaela; Stief, Christian G; Hennenberg, Martin

Selective inhibition of neurogenic, but not agonist-induced contractions by phospholipase A₂ inhibitors points to presynaptic phospholipase A₂ functions in contractile neurotransmission to human prostate smooth muscle.

Hu, Sheng; Huang, Ru; Keller, Patrick; Götz, Melanie; Tamalunas, Alexander; Weinhold, Philipp; Waidelich, Raphaela; Stief, Christian G; Hennenberg, Martin.

Afiliación

Hu S; Department of Urology, University Hospital, LMU Munich, Munich, Germany.
Huang R; Department of Urology, University Hospital, LMU Munich, Munich, Germany.
Keller P; Department of Urology, University Hospital, LMU Munich, Munich, Germany.
Götz M; Department of Urology, University Hospital, LMU Munich, Munich, Germany.
Tamalunas A; Department of Urology, University Hospital, LMU Munich, Munich, Germany.
Weinhold P; Department of Urology, University Hospital, LMU Munich, Munich, Germany.
Waidelich R; Department of Urology, University Hospital, LMU Munich, Munich, Germany.
Stief CG; Department of Urology, University Hospital, LMU Munich, Munich, Germany.
Hennenberg M; Department of Urology, University Hospital, LMU Munich, Munich, Germany.

Neurourol Urodyn ; 42(7): 1522-1531, 2023 09.

Article en En | MEDLINE | ID: mdl-37583250

Asunto(s)

Contracción Muscular; Próstata; Masculino; Humanos; Próstata/fisiología; Contracción Muscular/fisiología; Tromboxanos/farmacología; Transmisión Sináptica; Agonistas Adrenérgicos/farmacología; Músculo Liso; Adrenérgicos/farmacología; Fosfolipasas/farmacología

Palabras clave

benign prostatic hyperplasia (BPH); lower urinary tract symptoms (LUTS); phospholipase; prostate smooth muscle contraction; voiding symptoms; α1-adrenoceptor; α1-blocker

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Texto completo: 1 Base de datos: MEDLINE Asunto principal: Próstata / Contracción Muscular Idioma: En Revista: Neurourol Urodyn Año: 2023 Tipo del documento: Article

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Texto completo: 1 Base de datos: MEDLINE Asunto principal: Próstata / Contracción Muscular Idioma: En Revista: Neurourol Urodyn Año: 2023 Tipo del documento: Article