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Extended safety and tolerability of subcutaneous CAP256V2LS and VRC07-523LS in HIV-negative women: study protocol for the randomised, placebo-controlled double-blinded, phase 2 CAPRISA 012C trial.
Mahomed, Sharana; Garrett, Nigel; Potloane, Disebo; Sikazwe, Izukanji T; Capparelli, Edmund; Harkoo, Ishana; Gengiah, Tanuja Narayansamy; Zuma, Nonhlanhla Yende; Osman, Farzana; Mansoor, Leila; Archary, Derseree; Myeni, Nqobile; Radebe, Precious; Samsunder, Natasha; Doria-Rose, Nicole; Carlton, Kevin; Gama, Lucio; Koup, Richard A; Narpala, Sandeep; Serebryannyy, Leonid; Moore, Penny; Williamson, Carolyn; Pozzetto, Bruno; Hankins, Catherine; Morris, Lynn; Karim, Quarraisha Abdool; Abdool Karim, Salim.
Afiliación
  • Mahomed S; Centre for the AIDS Programme of Research in South Africa (CAPRISA), Durban, South Africa, Durban, South Africa Sharana.Mahomed@caprisa.org.
  • Garrett N; Centre for the AIDS Programme of Research in South Africa (CAPRISA), Durban, South Africa, Durban, South Africa.
  • Potloane D; Department of Public Health Medicine, School of Nursing and Public Health, University of KwaZulu-Natal, Durban, South Africa.
  • Sikazwe IT; Centre for the AIDS Programme of Research in South Africa (CAPRISA), Durban, South Africa, Durban, South Africa.
  • Capparelli E; Center for Infectious Disease Research, Lusaka, Zambia.
  • Harkoo I; University of California, La Jolla, California, USA.
  • Gengiah TN; Centre for the AIDS Programme of Research in South Africa (CAPRISA), Durban, South Africa, Durban, South Africa.
  • Zuma NY; Centre for the AIDS Programme of Research in South Africa (CAPRISA), Durban, South Africa, Durban, South Africa.
  • Osman F; Centre for the AIDS Programme of Research in South Africa (CAPRISA), Durban, South Africa, Durban, South Africa.
  • Mansoor L; Centre for the AIDS Programme of Research in South Africa (CAPRISA), Durban, South Africa, Durban, South Africa.
  • Archary D; Centre for the AIDS Programme of Research in South Africa (CAPRISA), Durban, South Africa, Durban, South Africa.
  • Myeni N; Centre for the AIDS Programme of Research in South Africa (CAPRISA), Durban, South Africa, Durban, South Africa.
  • Radebe P; Department of Medical Microbiology, School of Laboratory Medicine and Medical Science, University of KwaZulu-Natal, Durban, South Africa.
  • Samsunder N; Centre for the AIDS Programme of Research in South Africa (CAPRISA), Durban, South Africa, Durban, South Africa.
  • Doria-Rose N; Centre for the AIDS Programme of Research in South Africa (CAPRISA), Durban, South Africa, Durban, South Africa.
  • Carlton K; Centre for the AIDS Programme of Research in South Africa (CAPRISA), Durban, South Africa, Durban, South Africa.
  • Gama L; NIAID-VRC, National Institutes of Health, Bethesda, Maryland, USA.
  • Koup RA; NIAID-VRC, National Institutes of Health, Bethesda, Maryland, USA.
  • Narpala S; NIAID-VRC, National Institutes of Health, Bethesda, Maryland, USA.
  • Serebryannyy L; NIAID-VRC, National Institutes of Health, Bethesda, Maryland, USA.
  • Moore P; NIAID-VRC, National Institutes of Health, Bethesda, Maryland, USA.
  • Williamson C; NIAID-VRC, National Institutes of Health, Bethesda, Maryland, USA.
  • Pozzetto B; Centre for the AIDS Programme of Research in South Africa (CAPRISA), Durban, South Africa, Durban, South Africa.
  • Hankins C; National Institute for Communicable Diseases of the National Health Laboratory Services, Johannesburg, South Africa.
  • Morris L; SA MRC Antibody Immunity Research Unit, Faculty of Health Sciences, University of the Witwatersrand, Johannesburg, South Africa.
  • Karim QA; Centre for the AIDS Programme of Research in South Africa (CAPRISA), Durban, South Africa, Durban, South Africa.
  • Abdool Karim S; Division of Medical Virology, Institute of Infectious Disease and Molecular Medicine, University of Cape Town, University of Cape Townand National Health Laboratory Service, Cape Town, South Africa.
BMJ Open ; 13(8): e076843, 2023 08 28.
Article en En | MEDLINE | ID: mdl-37640457

Texto completo: 1 Base de datos: MEDLINE Asunto principal: Infecciones por VIH / Síndrome de Inmunodeficiencia Adquirida Tipo de estudio: Clinical_trials / Guideline País/Región como asunto: Africa Idioma: En Revista: BMJ Open Año: 2023 Tipo del documento: Article

Texto completo: 1 Base de datos: MEDLINE Asunto principal: Infecciones por VIH / Síndrome de Inmunodeficiencia Adquirida Tipo de estudio: Clinical_trials / Guideline País/Región como asunto: Africa Idioma: En Revista: BMJ Open Año: 2023 Tipo del documento: Article