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Exosomes derived from bone marrow mesenchymal stem cells regulate pyroptosis via the miR-143-3p/myeloid differentiation factor 88 axis to ameliorate intestinal ischemia-reperfusion injury.
Wan, Zhanhai; Zhang, Yan; Lv, Jipeng; Yuan, Yuan; Guo, Wenwen; Leng, Yufang.
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  • Wan Z; The First School of Clinical Medicine, Lanzhou University, Lanzhou, China.
  • Zhang Y; Department of Anesthesiology, The First Hospital of Lanzhou University, Lanzhou University, Lanzhou, China.
  • Lv J; The First School of Clinical Medicine, Lanzhou University, Lanzhou, China.
  • Yuan Y; Department of Anesthesiology, The First Hospital of Lanzhou University, Lanzhou University, Lanzhou, China.
  • Guo W; The First School of Clinical Medicine, Lanzhou University, Lanzhou, China.
  • Leng Y; Department of Anesthesiology, The First Hospital of Lanzhou University, Lanzhou University, Lanzhou, China.
Bioengineered ; 14(1): 2253414, 2023 12.
Article en En | MEDLINE | ID: mdl-37674357
BMSC-exos ameliorate intestinal ischemia/reperfusion (I/R) injurymiR-143-3p levels were reduced in I/R injury and increased with BMSC-exo treatmentmiR-143-3p directly targeted and downregulated the expression of MyD88BMSC-exos regulate pyroptosis in intestinal I/R injury via the miR-143-3p-MyD88 axis.
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Texto completo: 1 Base de datos: MEDLINE Asunto principal: Daño por Reperfusión / MicroARNs / Exosomas / Células Madre Mesenquimatosas Tipo de estudio: Prognostic_studies Idioma: En Revista: Bioengineered Año: 2023 Tipo del documento: Article
Texto completo
Imprimir
XML
PubMed Links
Buscar en Google

Texto completo: 1 Base de datos: MEDLINE Asunto principal: Daño por Reperfusión / MicroARNs / Exosomas / Células Madre Mesenquimatosas Tipo de estudio: Prognostic_studies Idioma: En Revista: Bioengineered Año: 2023 Tipo del documento: Article