Screening Campaign and Docking Investigations in Identifying New Hit Compounds as Inhibitors of Human Carbonic Anhydrases Expressed In Tumour Cells.

Ricci, Federico; Angeli, Andrea; Mancuso, Francesca; De Luca, Laura; Supuran, Claudiu T; Gitto, Rosaria

Ricci, Federico; Angeli, Andrea; Mancuso, Francesca; De Luca, Laura; Supuran, Claudiu T; Gitto, Rosaria.

Afiliación

Ricci F; CHIBIOFARAM Department, University of Messina, Viale F. d'Alcontres 31, 98166, Messina, Italy.
Angeli A; NEUROFARBA Department, University of Florence, Via Ugo Schiff 6, 50019, Sesto Fiorentino, Italy.
Mancuso F; CHIBIOFARAM Department, University of Messina, Viale F. d'Alcontres 31, 98166, Messina, Italy.
De Luca L; CHIBIOFARAM Department, University of Messina, Viale F. d'Alcontres 31, 98166, Messina, Italy.
Supuran CT; NEUROFARBA Department, University of Florence, Via Ugo Schiff 6, 50019, Sesto Fiorentino, Italy.
Gitto R; CHIBIOFARAM Department, University of Messina, Viale F. d'Alcontres 31, 98166, Messina, Italy.

ChemMedChem ; 18(20): e202300330, 2023 10 17.

Article en En | MEDLINE | ID: mdl-37694943

Asunto(s)

Anhidrasas Carbónicas; Neoplasias; Humanos; Relación Estructura-Actividad; Anhidrasas Carbónicas/metabolismo; Anhidrasa Carbónica IX/metabolismo; Antígenos de Neoplasias/metabolismo; Anhidrasa Carbónica I/metabolismo; Neoplasias/tratamiento farmacológico; Isoformas de Proteínas/metabolismo; Inhibidores de Anhidrasa Carbónica/química; Estructura Molecular; Microambiente Tumoral

Palabras clave

antitumor agents; arylsulfonamides; carbonic anhydrase; docking studies; molecular modeling

Texto completo

Imprimir

XML

PubMed Links

Buscar en Google

Texto completo: 1 Base de datos: MEDLINE Asunto principal: Anhidrasas Carbónicas / Neoplasias Tipo de estudio: Diagnostic_studies / Prognostic_studies / Screening_studies Idioma: En Revista: ChemMedChem Asunto de la revista: FARMACOLOGIA / QUIMICA Año: 2023 Tipo del documento: Article

Texto completo

Imprimir

XML

PubMed Links

Buscar en Google