Interferon-gamma and tumor necrosis factor-alpha synergistically enhance the immunosuppressive capacity of human umbilical-cord-derived mesenchymal stem cells by increasing PD-L1 expression.

Chen, Zhuo; Yao, Meng-Wei; Shen, Zhi-Lin; Li, Shi-Dan; Xing, Wei; Guo, Wei; Li, Zhan; Wu, Xiao-Feng; Ao, Luo-Quan; Lu, Wen-Yong; Lian, Qi-Zhou; Xu, Xiang; Ao, Xiang

Chen, Zhuo; Yao, Meng-Wei; Shen, Zhi-Lin; Li, Shi-Dan; Xing, Wei; Guo, Wei; Li, Zhan; Wu, Xiao-Feng; Ao, Luo-Quan; Lu, Wen-Yong; Lian, Qi-Zhou; Xu, Xiang; Ao, Xiang.

Afiliación

Chen Z; Department of Stem Cell & Regenerative Medicine, State Key Laboratory of Trauma, Burn and Combined Injury, Daping Hospital, Army Medical University, Chongqing 400042, China.
Yao MW; College of Basic Medical Sciences, Army Medical University, Chongqing 400038, China.
Shen ZL; Department of Stem Cell & Regenerative Medicine, State Key Laboratory of Trauma, Burn and Combined Injury, Daping Hospital, Army Medical University, Chongqing 400042, China.
Li SD; Department of Stem Cell & Regenerative Medicine, State Key Laboratory of Trauma, Burn and Combined Injury, Daping Hospital, Army Medical University, Chongqing 400042, China.
Xing W; Department of Orthopedics, Daping Hospital, Army Medical University, Chongqing 400042, China.
Guo W; Department of Stem Cell & Regenerative Medicine, State Key Laboratory of Trauma, Burn and Combined Injury, Daping Hospital, Army Medical University, Chongqing 400042, China.
Li Z; Department of Stem Cell & Regenerative Medicine, State Key Laboratory of Trauma, Burn and Combined Injury, Daping Hospital, Army Medical University, Chongqing 400042, China.
Wu XF; Department of Stem Cell & Regenerative Medicine, State Key Laboratory of Trauma, Burn and Combined Injury, Daping Hospital, Army Medical University, Chongqing 400042, China.
Ao LQ; Department of Stem Cell & Regenerative Medicine, State Key Laboratory of Trauma, Burn and Combined Injury, Daping Hospital, Army Medical University, Chongqing 400042, China.
Lu WY; Department of Stem Cell & Regenerative Medicine, State Key Laboratory of Trauma, Burn and Combined Injury, Daping Hospital, Army Medical University, Chongqing 400042, China.
Lian QZ; Department of Hepatobiliary Surgery, The First Affiliated Hospital of Wenzhou Medical University, The South of Shangcai Village, Wenzhou 325005, Zhejiang Province, China.
Xu X; Department of Medicine, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Hong Kong 999077, China.
Ao X; Department of Stem Cell & Regenerative Medicine, State Key Laboratory of Trauma, Burn and Combined Injury, Daping Hospital, Army Medical University, Chongqing 400042, China.

World J Stem Cells ; 15(8): 787-806, 2023 Aug 26.

Article en En | MEDLINE | ID: mdl-37700823

Palabras clave

Human umbilical-cord-derived mesenchymal stem cells; Immunomodulation; Interferon-gamma; Programmed cell death 1 ligand 1; Tumor necrosis factor-alpha; Ulcerative colitis

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