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Dynamic extracellular vestibule of human SERT: Unveiling druggable potential with high-affinity allosteric inhibitors.
Salomon, Kristine; Abramyan, Ara M; Plenge, Per; Wang, Lingle; Bundgaard, Christoffer; Bang-Andersen, Benny; Loland, Claus J; Shi, Lei.
Afiliación
  • Salomon K; Laboratory for Membrane Protein Dynamics, Department of Neuroscience, Faculty of Health and Medical Sciences, University of Copenhagen, DK-2200 Copenhagen N, Denmark.
  • Abramyan AM; Computational Chemistry and Molecular Biophysics Section, Molecular Targets and Medications Discovery Branch, National Institute on Drug Abuse - Intramural Research Program, NIH, Baltimore, MD 21224.
  • Plenge P; Schrödinger, Inc., San Diego, CA 92121.
  • Wang L; Laboratory for Membrane Protein Dynamics, Department of Neuroscience, Faculty of Health and Medical Sciences, University of Copenhagen, DK-2200 Copenhagen N, Denmark.
  • Bundgaard C; Schrödinger, Inc., New York, NY 10036.
  • Bang-Andersen B; Medicinal Chemistry and Translational DMPK, H. Lundbeck A/S, DK-2500 Copenhagen-Valby, Denmark.
  • Loland CJ; Medicinal Chemistry and Translational DMPK, H. Lundbeck A/S, DK-2500 Copenhagen-Valby, Denmark.
  • Shi L; Laboratory for Membrane Protein Dynamics, Department of Neuroscience, Faculty of Health and Medical Sciences, University of Copenhagen, DK-2200 Copenhagen N, Denmark.
Proc Natl Acad Sci U S A ; 120(41): e2304089120, 2023 10 10.
Article en En | MEDLINE | ID: mdl-37792512
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Texto completo: 1 Base de datos: MEDLINE Asunto principal: Citalopram / Proteínas de Transporte de Serotonina en la Membrana Plasmática Tipo de estudio: Prognostic_studies Idioma: En Revista: Proc Natl Acad Sci U S A Año: 2023 Tipo del documento: Article
Texto completo
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Texto completo: 1 Base de datos: MEDLINE Asunto principal: Citalopram / Proteínas de Transporte de Serotonina en la Membrana Plasmática Tipo de estudio: Prognostic_studies Idioma: En Revista: Proc Natl Acad Sci U S A Año: 2023 Tipo del documento: Article