The presence of Rickettsia felis in communities in the central highlands of Vietnam.
Acta Trop
; 248: 107034, 2023 Dec.
Article
en En
| MEDLINE
| ID: mdl-37793492
ABSTRACT
Rickettsia felis is an emerging flea-borne spotted fever pathogen that causes febrile illness in humans. In Vietnam, R. felis was detected in hospitalized patients, but there is no information on its presence in the Vietnamese community. This cross-sectional study aimed to determine the presence of R. felis in humans of the Central Highlands of Vietnam. A total of 158 blood and 213 serum samples were subjected to PCR and IFAT, respectively, to detect the presence of R. felis DNA and antibodies against R. felis. PCR assays detected R. felis DNA in four out of 158 blood samples, accounting for a prevalence of 2.53 % (95 % CI 0.81 %-6.76 %). Phylogenetic analysis indicated the presence of R. felis and R. felis genotype RF2125 in the communities in the Central Highlands of Vietnam. The result of IFAT identified seven out of 213 serum samples (3.29 %, 95 % CI 1.45 %-6.93 %) positive for antibodies against R. felis. This study was the first to demonstrate the presence of active R. felis infections in the communities in the Central Highlands of Vietnam utilizing both molecular and serological methods.
Palabras clave
Texto completo:
1
Base de datos:
MEDLINE
Asunto principal:
Rickettsia
/
Infecciones por Rickettsia
/
Rickettsia felis
/
Siphonaptera
Tipo de estudio:
Observational_studies
/
Risk_factors_studies
País/Región como asunto:
Asia
Idioma:
En
Revista:
Acta Trop
Año:
2023
Tipo del documento:
Article