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Virulence profiling of Cryptococcus gattii isolates in China: insights from a multi-center study.
Zang, Xuelei; Ke, Weixin; Huang, Yemei; Yang, Chen; Song, Jialin; Deng, Hengyu; Zhou, Meng; Wang, Qiqi; Zhou, Yangyu; Dai, Bin; Qian, Jin; Shen, Dingxia; Wang, Linqi; Xue, Xinying.
Afiliación
  • Zang X; Department of Respiratory and Critical Care, Emergency and Critical Care Medical Center, Beijing Shijitan Hospital, Capital Medical University , Beijing, China.
  • Ke W; State Key Laboratory of Mycology, Institute of Microbiology, Chinese Academy of Sciences , Beijing, China.
  • Huang Y; Department of Respiratory and Critical Care, Emergency and Critical Care Medical Center, Beijing Shijitan Hospital, Capital Medical University , Beijing, China.
  • Yang C; Capital Medical University , Beijing, China.
  • Song J; Medical School of Chinese PLA , Beijing, China.
  • Deng H; Medical Laboratory Center, The First Medical Centre, Chinese PLA General Hospital , Beijing, China.
  • Zhou M; Weifang Medical University , Weifang, China.
  • Wang Q; Weifang Medical University , Weifang, China.
  • Zhou Y; School of Medical Imaging, Binzhou Medical University , Yantai, China.
  • Dai B; Department of Respiratory and Critical Care, Emergency and Critical Care Medical Center, Beijing Shijitan Hospital, Capital Medical University , Beijing, China.
  • Qian J; Department of Respiratory and Critical Care, Emergency and Critical Care Medical Center, Beijing Shijitan Hospital, Capital Medical University , Beijing, China.
  • Shen D; Capital Medical University , Beijing, China.
  • Wang L; Department of Neurosurgery, Beijing Shijitan Hospital, Capital Medical University , Beijing, China.
  • Xue X; Department of Respiratory and Critical Care, Emergency and Critical Care Medical Center, Beijing Shijitan Hospital, Capital Medical University , Beijing, China.
Microbiol Spectr ; 11(6): e0244323, 2023 Dec 12.
Article en En | MEDLINE | ID: mdl-37905820
IMPORTANCE: Our study indicates that the molecular typing of Cryptococcus gattii is unrelated to virulence. The integration of animal experiments and clinical prognosis demonstrated that pathogenicity did not exhibit a direct correlation with in vitro virulence phenotypes or molecular genotypes, emphasizing the intricate nature of virulence. In conclusion, our research holds the potential to provide valuable insights into understanding the microbiological attributes of C. gattii in China.
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Texto completo: 1 Base de datos: MEDLINE Asunto principal: Criptococosis / Cryptococcus neoformans / Cryptococcus gattii País/Región como asunto: Asia Idioma: En Revista: Microbiol Spectr Año: 2023 Tipo del documento: Article
Texto completo
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Texto completo: 1 Base de datos: MEDLINE Asunto principal: Criptococosis / Cryptococcus neoformans / Cryptococcus gattii País/Región como asunto: Asia Idioma: En Revista: Microbiol Spectr Año: 2023 Tipo del documento: Article