The Ultraviolet Irradiation of Keratinocytes Induces Ectopic Expression of LINE-1 Retrotransposon Machinery and Leads to Cellular Senescence.

Touma, Fadi; Lambert, Marine; Martínez Villarreal, Amelia; Gantchev, Jennifer; Ramchatesingh, Brandon; Litvinov, Ivan V

Touma, Fadi; Lambert, Marine; Martínez Villarreal, Amelia; Gantchev, Jennifer; Ramchatesingh, Brandon; Litvinov, Ivan V.

Afiliación

Touma F; Research Institute, McGill University Health Centre, McGill University, Montreal, QC H4A 3J1, Canada.
Lambert M; Faculty of Medicine and Health Sciences, McGill University, Montreal, QC H3G 2M1, Canada.
Martínez Villarreal A; Research Institute, McGill University Health Centre, McGill University, Montreal, QC H4A 3J1, Canada.
Gantchev J; Research Institute, McGill University Health Centre, McGill University, Montreal, QC H4A 3J1, Canada.
Ramchatesingh B; Research Institute, McGill University Health Centre, McGill University, Montreal, QC H4A 3J1, Canada.
Litvinov IV; Research Institute, McGill University Health Centre, McGill University, Montreal, QC H4A 3J1, Canada.

Biomedicines ; 11(11)2023 Nov 10.

Article en En | MEDLINE | ID: mdl-38002016

Palabras clave

BB-UVB; HaCaT; N/TERT1; NB-UVB; cellular senescence; genomic instability; keratinocytes; long interspersed nucleotide element-1 (LINE-1); miR-16; microRNAs; phototherapy

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