Dynamic monitoring of an enzymatically driven dissipative toehold-mediated strand displacement reaction.

Li, Shuang; Zhao, Disong; Yang, Fangfang; Liu, Shufeng

Li, Shuang; Zhao, Disong; Yang, Fangfang; Liu, Shufeng.

Afiliación

Li S; College of Chemistry and Chemical Engineering, Yantai University, 30 Qingquan Road, Yantai 264005, China. yangfangfang@ytu.edu.cn.
Zhao D; College of Chemistry and Chemical Engineering, Yantai University, 30 Qingquan Road, Yantai 264005, China. yangfangfang@ytu.edu.cn.
Yang F; College of Chemistry and Chemical Engineering, Yantai University, 30 Qingquan Road, Yantai 264005, China. yangfangfang@ytu.edu.cn.
Liu S; College of Chemistry and Chemical Engineering, Yantai University, 30 Qingquan Road, Yantai 264005, China. yangfangfang@ytu.edu.cn.

Chem Commun (Camb) ; 60(5): 570-573, 2024 Jan 11.

Article en En | MEDLINE | ID: mdl-38093688

ABSTRACT

ABSTRACT

A general strategy to program self-resettable and dissipative toehold-mediated strand displacement reactions was proposed, using DNA strands as the fuel and lambda exonuclease as the fuel-consuming unit. This non-equilibrium system is reversible and temporally controllable. Furthermore, it can be well integrated into a DNA network to temporally control its cascade reaction or dynamic behaviour.

Asunto(s)

ADN; Recombinación Genética; ADN/genética

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Texto completo: 1 Base de datos: MEDLINE Asunto principal: Recombinación Genética / ADN Idioma: En Revista: Chem Commun (Camb) Asunto de la revista: QUIMICA Año: 2024 Tipo del documento: Article

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