Role of ultrasound in detection of lymph-node metastasis in gynecological cancer: systematic review and meta-analysis.
Ultrasound Obstet Gynecol
; 64(2): 155-163, 2024 Aug.
Article
en En
| MEDLINE
| ID: mdl-38452144
ABSTRACT
OBJECTIVE:
To assess the diagnostic performance of transvaginal sonography (TVS) for the preoperative evaluation of lymph-node metastasis in gynecological cancer.METHODS:
This was a systematic review and meta-analysis of studies published between January 1990 and May 2023 evaluating the role of ultrasound in detecting pelvic lymph-node metastasis (index test) in gynecological cancer, using histopathological analysis as the reference standard. The quality of included studies was assessed using the Quality Assessment of Diagnostic Accuracy Studies-2 tool. Pooled sensitivity, specificity and diagnostic odds ratio were estimated.RESULTS:
The literature search identified 2638 citations. Eight studies reporting on a total of 967 women were included. The mean prevalence of pelvic lymph-node metastasis was 24.2% (range, 14.0-65.6%). The risk of bias was low for most domains assessed. Pooled sensitivity, specificity and diagnostic odds ratio of TVS were 41% (95% CI, 26-58%), 98% (95% CI, 93-99%) and 32 (95% CI, 14-72), respectively. High heterogeneity was found between studies for both sensitivity and specificity.CONCLUSION:
TVS showed a high pooled specificity for the detection of pelvic lymph-node metastasis in gynecological cancer, but pooled sensitivity was low. © 2024 The Authors. Ultrasound in Obstetrics & Gynecology published by John Wiley & Sons Ltd on behalf of International Society of Ultrasound in Obstetrics and Gynecology.Palabras clave
Texto completo:
1
Base de datos:
MEDLINE
Asunto principal:
Ultrasonografía
/
Sensibilidad y Especificidad
/
Neoplasias de los Genitales Femeninos
/
Ganglios Linfáticos
/
Metástasis Linfática
Idioma:
En
Revista:
Ultrasound Obstet Gynecol
/
Ultrasound in obstetrics and gynecology
/
Ultrasound obstet. gynecol
Asunto de la revista:
DIAGNOSTICO POR IMAGEM
/
GINECOLOGIA
/
OBSTETRICIA
Año:
2024
Tipo del documento:
Article