The association between patterns of weight change, diabetes status and glycaemia among adults with overweight and obesity.
Diabetes Res Clin Pract
; 210: 111607, 2024 Apr.
Article
en En
| MEDLINE
| ID: mdl-38453059
ABSTRACT
AIMS:
To investigate the associations between weight change patterns and 5-year incident non-diabetic hyperglycaemia (NDH), and glycated haemoglobin (HbA1c) levels among individuals who had overweight or obesity.METHODS:
This longitudinal cohort study (N = 435) pooled data from a weight management trial. Participants were adults with a body mass index of ≥28 kg/m2. They were categorised as "no weight loss", "maintainers", and "regainers" based on their weight at 3 months and 12 months after baseline. Multivariable logistic regression models and linear regressions were conducted to examine the associations.RESULTS:
Between 1-year and 5-year follow-ups, 77 participants developed NDH. We found no statistically significant association between weight change patterns and incident NDH at 5 years. Among weight loss maintainers, mean HbA1c was -0.15% (95% confidence intervals (CI) -0.22, -0.10) lower after 1 year and -0.15% (95% CI -0.23, -0.06) lower after 5 years compared to the no weight loss group. There was no difference between weight loss regainers and no weight loss group in HbA1c levels.CONCLUSIONS:
Compared to those who did not lose weight, participants who maintained their weight loss had lower HbA1c levels after 1 year and 5 years, which highlights the importance of providing long-term support to prevent weight regain.Palabras clave
Texto completo:
1
Base de datos:
MEDLINE
Asunto principal:
Diabetes Mellitus Tipo 2
/
Hiperglucemia
Idioma:
En
Revista:
Diabetes Res Clin Pract
/
Diabetes research and clinical practice (Online)
Asunto de la revista:
ENDOCRINOLOGIA
Año:
2024
Tipo del documento:
Article