[Cost-effectiveness analysis of fracture liaison services in Catalonia]. / Análisis de coste-efectividad de las Unidades de Coordinación de Fracturas en Cataluña.
J Healthc Qual Res
; 39(4): 205-213, 2024.
Article
en Es
| MEDLINE
| ID: mdl-38614935
ABSTRACT
OBJECTIVE:
To assess the cost-effectiveness of Fracture Liaison Service (FLS) compared to the standard of care for secondary prevention of fragility fractures form the perspective of the Catalan Health Service.METHODS:
Cost-utility assessment through a Markov model that simulated disease progression of a patients' cohort candidates to initiate antiosteoporotic treatment after a fragility fracture. A time horizon of 10 years and a 6-month duration per cycle was established. Clinical, economics and quality of life parameters were obtained from the literature and derived from four Catalan FLS. The Catalan Health Service perspective was adopted, considering direct health costs expressed in 2022 euros. A 3% discount rate was applied on costs and outcomes. Uncertainty was assessed through multiple sensitivity analyses.RESULTS:
Compared to the standard of care, FLS would promote antiosteoporotic initiation and persistence, reducing the incidence and mortality associated with subsequent fragility fractures. This incremental clinical benefit was estimated at 0.055 years and 0.112 quality-adjusted life years (QALYs) per patient. A higher cost (1,073.79 per patient) was estimated, resulting into an incremental cost-utility ratio of 9,602.72 per QALYs gained. The sensitivity analyses performed were consistent, corroborating the robustness and conservative approach of the base-case.CONCLUSIONS:
The introduction of FLS for the secondary prevention of FF would represent a cost-effective strategy from the Catalan Health Service perspective.Palabras clave
Análisis coste-beneficio; Bone; Catalonia; Cataluña; Cost-Benefit Analysis; Delivery of Health Care; Economics; Efficiency; Eficiencia; Farmacoeconomía; Fracturas osteoporóticas; Fracturas óseas; Fractures; Osteoporosis; Osteoporotic Fractures; Pharmaceutical; Prestación de atención de salud; Prevención secundaria; Secondary Prevention
Texto completo:
1
Base de datos:
MEDLINE
Asunto principal:
Cadenas de Markov
/
Análisis Costo-Beneficio
/
Años de Vida Ajustados por Calidad de Vida
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Prevención Secundaria
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Fracturas Osteoporóticas
País/Región como asunto:
Europa
Idioma:
Es
Revista:
J Healthc Qual Res
Año:
2024
Tipo del documento:
Article