Case of IgG4-related Disease with Crescentic Glomerulonephritis: An Unusual Presentation of the Disease.
Iran J Kidney Dis
; 18(2): 133-135, 2024 03.
Article
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| MEDLINE
| ID: mdl-38660697
ABSTRACT
IgG4-related disease (IgG4-RD) is a chronic systemic inflammatory disease, characterized by tissue infiltration of lymphocytes and IgG4-secreting plasma cells, presenting by fibrosis of different tissues, which is usually responsive only to oral steroids therapy. Kidneys are the most commonly involved organs, exhibiting renal insufficiency, tubulointerstitial nephritis, and glomerulonephritis. Here, we describe a patient with acute renal insufficiency who was presented with edema, weakness, anemia and multiple lymphadenopathies. Kidney and lymph node biopsy showed crescentic glomerulonephritis in kidneys and lymphoplasmacytic infiltration in lymph nodes. After a course of treatment with an intravenous pulse of corticosteroid and cyclophosphamide, the patient's symptoms subsided, and kidney function improved. DOI 10.52547/ijkd.7788.
Texto completo:
1
Base de datos:
MEDLINE
Asunto principal:
Ciclofosfamida
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Enfermedad Relacionada con Inmunoglobulina G4
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Glomerulonefritis
Idioma:
En
Revista:
Iran J Kidney Dis
Asunto de la revista:
NEFROLOGIA
Año:
2024
Tipo del documento:
Article