[Research progress on bioinformatics in pulmonary arterial hypertension]. / çç©ä¿¡æ¯å¦å¨èºå¨èé«åä¸çç 究è¿å±.
Zhongguo Dang Dai Er Ke Za Zhi
; 26(4): 425-431, 2024 Apr 15.
Article
en Zh
| MEDLINE
| ID: mdl-38660909
ABSTRACT
Pulmonary arterial hypertension (PAH) is a severe disease characterized by abnormal pulmonary vascular remodeling and increased right ventricular pressure load, posing a significant threat to patient health. While some pathological mechanisms of PAH have been revealed, the deeper mechanisms of pathogenesis remain to be elucidated. In recent years, bioinformatics has provided a powerful tool for a deeper understanding of the complex mechanisms of PAH through the integration of techniques such as multi-omics analysis, artificial intelligence, and Mendelian randomization. This review focuses on the bioinformatics methods and technologies used in PAH research, summarizing their current applications in the study of disease mechanisms, diagnosis, and prognosis assessment. Additionally, it analyzes the existing challenges faced by bioinformatics and its potential applications in the clinical and basic research fields of PAH in the future.
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Texto completo:
1
Base de datos:
MEDLINE
Asunto principal:
Biología Computacional
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Hipertensión Arterial Pulmonar
Idioma:
Zh
Revista:
Zhongguo Dang Dai Er Ke Za Zhi
Año:
2024
Tipo del documento:
Article