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Genomic factors shape carbon and nitrogen metabolic niche breadth across Saccharomycotina yeasts.
Opulente, Dana A; LaBella, Abigail Leavitt; Harrison, Marie-Claire; Wolters, John F; Liu, Chao; Li, Yonglin; Kominek, Jacek; Steenwyk, Jacob L; Stoneman, Hayley R; VanDenAvond, Jenna; Miller, Caroline R; Langdon, Quinn K; Silva, Margarida; Gonçalves, Carla; Ubbelohde, Emily J; Li, Yuanning; Buh, Kelly V; Jarzyna, Martin; Haase, Max A B; Rosa, Carlos A; CCadez, Neza; Libkind, Diego; DeVirgilio, Jeremy H; Hulfachor, Amanda Beth; Kurtzman, Cletus P; Sampaio, José Paulo; Gonçalves, Paula; Zhou, Xiaofan; Shen, Xing-Xing; Groenewald, Marizeth; Rokas, Antonis; Hittinger, Chris Todd.
Afiliación
  • Opulente DA; Laboratory of Genetics, Wisconsin Energy Institute, Center for Genomic Science Innovation, J. F. Crow Institute for the Study of Evolution, University of Wisconsin-Madison, Madison, WI 53726, USA.
  • LaBella AL; DOE Great Lakes Bioenergy Research Center, University of Wisconsin-Madison, Madison, WI 53726, USA.
  • Harrison MC; Biology Department, Villanova University, Villanova, PA 19085, USA.
  • Wolters JF; Department of Biological Sciences, Vanderbilt University, Nashville, TN 37235, USA.
  • Liu C; Evolutionary Studies Initiative, Vanderbilt University, Nashville, TN 37235, USA.
  • Li Y; North Carolina Research Center (NCRC), Department of Bioinformatics and Genomics, The University of North Carolina at Charlotte, Kannapolis, NC 28081, USA.
  • Kominek J; Department of Biological Sciences, Vanderbilt University, Nashville, TN 37235, USA.
  • Steenwyk JL; Evolutionary Studies Initiative, Vanderbilt University, Nashville, TN 37235, USA.
  • Stoneman HR; Laboratory of Genetics, Wisconsin Energy Institute, Center for Genomic Science Innovation, J. F. Crow Institute for the Study of Evolution, University of Wisconsin-Madison, Madison, WI 53726, USA.
  • VanDenAvond J; DOE Great Lakes Bioenergy Research Center, University of Wisconsin-Madison, Madison, WI 53726, USA.
  • Miller CR; College of Agriculture and Biotechnology and Centre for Evolutionary and Organismal Biology, Zhejiang University, Hangzhou 310058, China.
  • Langdon QK; Guangdong Province Key Laboratory of Microbial Signals and Disease Control, Integrative Microbiology Research Center, South China Agricultural University, Guangzhou 510642, China.
  • Silva M; Laboratory of Genetics, Wisconsin Energy Institute, Center for Genomic Science Innovation, J. F. Crow Institute for the Study of Evolution, University of Wisconsin-Madison, Madison, WI 53726, USA.
  • Gonçalves C; DOE Great Lakes Bioenergy Research Center, University of Wisconsin-Madison, Madison, WI 53726, USA.
  • Ubbelohde EJ; LifeMine Therapeutics, Inc., Cambridge, MA 02140, USA.
  • Li Y; Department of Biological Sciences, Vanderbilt University, Nashville, TN 37235, USA.
  • Buh KV; Evolutionary Studies Initiative, Vanderbilt University, Nashville, TN 37235, USA.
  • Jarzyna M; Howard Hughes Medical Institute and the Department of Molecular and Cell Biology, University of California, Berkeley, Berkeley, CA 94720, USA.
  • Haase MAB; Laboratory of Genetics, Wisconsin Energy Institute, Center for Genomic Science Innovation, J. F. Crow Institute for the Study of Evolution, University of Wisconsin-Madison, Madison, WI 53726, USA.
  • Rosa CA; DOE Great Lakes Bioenergy Research Center, University of Wisconsin-Madison, Madison, WI 53726, USA.
  • CCadez N; University of Colorado Anschutz Medical Campus, Aurora, CO 80045, USA.
  • Libkind D; Laboratory of Genetics, Wisconsin Energy Institute, Center for Genomic Science Innovation, J. F. Crow Institute for the Study of Evolution, University of Wisconsin-Madison, Madison, WI 53726, USA.
  • DeVirgilio JH; DOE Great Lakes Bioenergy Research Center, University of Wisconsin-Madison, Madison, WI 53726, USA.
  • Hulfachor AB; Laboratory of Genetics, Wisconsin Energy Institute, Center for Genomic Science Innovation, J. F. Crow Institute for the Study of Evolution, University of Wisconsin-Madison, Madison, WI 53726, USA.
  • Kurtzman CP; DOE Great Lakes Bioenergy Research Center, University of Wisconsin-Madison, Madison, WI 53726, USA.
  • Sampaio JP; Laboratory of Genetics, Wisconsin Energy Institute, Center for Genomic Science Innovation, J. F. Crow Institute for the Study of Evolution, University of Wisconsin-Madison, Madison, WI 53726, USA.
  • Gonçalves P; UCIBIO, Department of Life Sciences, NOVA School of Science and Technology, Universidade NOVA de Lisboa, Caparica, Portugal.
  • Zhou X; Associate Laboratory i4HB, NOVA School of Science and Technology, Universidade NOVA de Lisboa, Caparica, Portugal.
  • Shen XX; Laboratory of Genetics, Wisconsin Energy Institute, Center for Genomic Science Innovation, J. F. Crow Institute for the Study of Evolution, University of Wisconsin-Madison, Madison, WI 53726, USA.
  • Groenewald M; Department of Biological Sciences, Vanderbilt University, Nashville, TN 37235, USA.
  • Rokas A; Evolutionary Studies Initiative, Vanderbilt University, Nashville, TN 37235, USA.
  • Hittinger CT; UCIBIO, Department of Life Sciences, NOVA School of Science and Technology, Universidade NOVA de Lisboa, Caparica, Portugal.
Science ; 384(6694): eadj4503, 2024 Apr 26.
Article en En | MEDLINE | ID: mdl-38662846
ABSTRACT
Organisms exhibit extensive variation in ecological niche breadth, from very narrow (specialists) to very broad (generalists). Two general paradigms have been proposed to explain this variation (i) trade-offs between performance efficiency and breadth and (ii) the joint influence of extrinsic (environmental) and intrinsic (genomic) factors. We assembled genomic, metabolic, and ecological data from nearly all known species of the ancient fungal subphylum Saccharomycotina (1154 yeast strains from 1051 species), grown in 24 different environmental conditions, to examine niche breadth evolution. We found that large differences in the breadth of carbon utilization traits between yeasts stem from intrinsic differences in genes encoding specific metabolic pathways, but we found limited evidence for trade-offs. These comprehensive data argue that intrinsic factors shape niche breadth variation in microbes.
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Texto completo: 1 Base de datos: MEDLINE Asunto principal: Ascomicetos / Carbono / Interacción Gen-Ambiente / Nitrógeno Idioma: En Revista: Science Año: 2024 Tipo del documento: Article
Texto completo
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XML
PubMed Links
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Texto completo: 1 Base de datos: MEDLINE Asunto principal: Ascomicetos / Carbono / Interacción Gen-Ambiente / Nitrógeno Idioma: En Revista: Science Año: 2024 Tipo del documento: Article