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Evaluation of the Impact of Exposure To Heat and to By-Products of Combustion on the Health of Firefighters.
Boggi, A C; do Amaral, J B; Bacchi, A L L; Nascimento, V M; Voegels, R L; Dos Santos, J M B; Grimaldi, G; Basseto de Oliveira Araújo, K; Pavão, V; Passaretti, D A; Aldred, A; Gomes, G; Pezato, R.
Afiliación
  • Boggi AC; ENT Research Lab, Department of Otorhinolaryngology and Head and Neck Surgery, Federal University of São Paulo, São Paulo, Brazil.
  • do Amaral JB; Fire Department, Escola Superior de Bombeiros -- Polícia Militar do Estado de São Paulo, Franco da Rocha, Brazil.
  • Bacchi ALL; ENT Research Lab, Department of Otorhinolaryngology and Head and Neck Surgery, Federal University of São Paulo, São Paulo, Brazil.
  • Nascimento VM; ENT Research Lab, Department of Otorhinolaryngology and Head and Neck Surgery, Federal University of São Paulo, São Paulo, Brazil.
  • Voegels RL; Post-Graduation Program in Health Sciences, Santo Amaro University (UNISA), São Paulo, Brazil.
  • Dos Santos JMB; Fire Department, Escola Superior de Bombeiros -- Polícia Militar do Estado de São Paulo, Franco da Rocha, Brazil.
  • Grimaldi G; Department of Ophthalmology and Otorhinolaryngology, University of São Paulo, São Paulo, Brazil.
  • Basseto de Oliveira Araújo K; ENT Research Lab, Department of Otorhinolaryngology and Head and Neck Surgery, Federal University of São Paulo, São Paulo, Brazil.
  • Pavão V; Post-Graduation Program in Science of Human and Rehabilitation, Federal University of São Paulo (UNIFESP), Santos, Brazil.
  • Passaretti DA; Hospital da Polícia Militar, Polícia Militar do Estado de São Paulo, São Paulo, Brazil.
  • Aldred A; Hospital da Polícia Militar, Polícia Militar do Estado de São Paulo, São Paulo, Brazil.
  • Gomes G; Fire Department, Escola Superior de Bombeiros -- Polícia Militar do Estado de São Paulo, Franco da Rocha, Brazil.
  • Pezato R; Fire Department, Escola Superior de Bombeiros -- Polícia Militar do Estado de São Paulo, Franco da Rocha, Brazil.
Ann Burns Fire Disasters ; 36(2): 100-110, 2023 Jun.
Article en En | MEDLINE | ID: mdl-38681946
ABSTRACT
Firefighters are often exposed to high temperatures and by-products of combustion, which can affect their health. In this study, we assessed the impact of acute exposure of firefighters in fire simulators. Twenty male firefighters were exposed to fire simulators, and observed in four phases pre-exposure (group 0, control) and after the end of the first (group 1), second (group 2), and fourth (group 3) weeks of training. Blood samples were collected and dosed to evaluate the response of the immune, inflammatory (C-reactive protein, IL6, and IL10), and endocrine systems (cortisone, total testosterone, free testosterone, SHBG, bioavailable testosterone, TSH, and free T4). In groups 0, 1, and 3, a thermographic evaluation was also carried out to study the temperature and body heat flow of the participants. Regarding the inflammatory process, an increase in C-reactive protein and a reduction in IL-10 were observed. With respect to hormonal markers, an increase in cortisol and reduced levels of free T4 and bioavailable testosterone were found after exposure, with recovery of testosterone levels in the final week of training. Thermoregulatory adaptation of the organism has been associated with changes in heat flow in the organism in people subjected to extreme temperatures, with emphasis on the performance of the lower limbs. Our findings demonstrate an inflammatory response with hormonal changes after exposure to fire and an adaptive response of thermal balance, which could aid understanding of the physiology of the human body in extreme situations.
Les sapeurs-pompiers (SP) sont régulièrement exposés à la chaleur et aux produits de combustion, qui peuvent avoir un retentissement sur leur santé. Nous avons évalué l'effet d'une exposition aiguë de 22 SP (tous des hommes) à incendie simulé grâce à la répétition à 4 reprises d'une même batterie d'examens (avant- T0, et à la fin des 1ère -T1 2ème - T2 et 3ème - T3 semaines d'entraînement). Des paramètres sanguins relatifs à l'inflammation et l'immunité (CRP, IL6, IL10) ainsi qu'au système endocrinien (cortisol, testostérones totale, libre et biodisponible, SHBG, TSH et T4 libre) étaient prélevés à chaque évaluation. Une étude thermographique, évaluant la température corporelle et le flux thermique corporel était réalisée à T0, T1 et T3. On constatait une augmentation de la CRP et une baisse de IL10. On observait une augmentation de la cortisolémie ainsi qu'une baisse de thyroxine libre et testostérone biodisponible, cette dernière se normalisant à T3. L'adaptation corporelle à la chaleur se traduit par une augmentation du flux thermique, en particulier aux membres inférieurs. Nous observons donc des réponses inflammatoire comme endocrinienne et une adaptation de la thermorégulation en cas d'exposition à un incendie, constatations pouvant contribuer à la compréhension de la physiologie humaine en situations extrêmes.
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Texto completo: 1 Base de datos: MEDLINE Idioma: En Revista: Ann Burns Fire Disasters Año: 2023 Tipo del documento: Article

Texto completo: 1 Base de datos: MEDLINE Idioma: En Revista: Ann Burns Fire Disasters Año: 2023 Tipo del documento: Article