Comparison of corneal endothelial cell loss in FLACS: impact on endothelial cells in different regions.
J Cataract Refract Surg
; 50(9): 912-918, 2024 Sep 01.
Article
en En
| MEDLINE
| ID: mdl-38711211
ABSTRACT
PURPOSE:
To compare changes in corneal endothelial parameters after femtosecond laser-assisted cataract surgery (FLACS) and conventional phacoemulsification surgery (CPS) in different corneal regions.SETTING:
Chang Gung Memorial Hospital, Linkou, Taiwan.DESIGN:
Single-center, retrospective.METHODS:
Before and 1, 3, and 6 months postoperatively, specular microscopy was performed to measure endothelial cell density (ECD), corneal thickness, hexagonal cell rate (Hex), and coefficient of variation (CoV). Position 1 referred to the central cornea, position 2 was nearest to the main wound, and position 3 was at the peripheral zone diagonal to the main wound.RESULTS:
This study analyzed 96 eyes in the FLACS group and 110 eyes in the CPS group. Preoperatively, position 1 had lower ECD and CoV and higher Hex compared with the peripheral regions. FLACS patients had a significantly less phacoemulsification time and cumulative dissipated energy. At 1 month, FLACS patients showed a significantly smaller increase in corneal thickness at positions 1 and 2. At 3 months, FLACS patients had lower endothelial cell loss (ECL) at positions 1 and 3. ECL remained lower in FLACS patients at 6 months. The highest ECL was observed at position 2 in both groups and was progressive up to 6 months.CONCLUSIONS:
After phacoemulsification, ECL varied in different corneal regions. At 3 months, the FLACS group exhibited significantly less ECL at the central cornea; however, the continued ECL at 6 months near the main wound suggested ongoing endothelial remodeling in the region.
Texto completo:
1
Base de datos:
MEDLINE
Asunto principal:
Endotelio Corneal
/
Facoemulsificación
/
Pérdida de Celulas Endoteliales de la Córnea
Idioma:
En
Revista:
J Cataract Refract Surg
Asunto de la revista:
OFTALMOLOGIA
Año:
2024
Tipo del documento:
Article