Nucleic acids in modern molecular therapies: A realm of opportunities for strategic drug design.
Curr Opin Struct Biol
; 87: 102838, 2024 Aug.
Article
en En
| MEDLINE
| ID: mdl-38759298
ABSTRACT
RNA vaccines have made evident to society what was already known by the scientific community nucleic acids will be the "drugs of the future." By modifying the genome, interfering in transcription or translation, and by introducing new catalysts into the cell or by mimicking antibody effects, nucleic acids can generate therapeutic activities that are not accessible by any other therapeutic agents. There are, however, challenges that need to be solved in the next few years to make nucleic acids usable in a wide range of therapeutic scenarios. This review illustrates how simulation methods can help achieve this goal.
Texto completo:
1
Base de datos:
MEDLINE
Asunto principal:
Ácidos Nucleicos
/
Diseño de Fármacos
Idioma:
En
Revista:
Curr Opin Struct Biol
Asunto de la revista:
BIOLOGIA MOLECULAR
Año:
2024
Tipo del documento:
Article