Obesity increases the risk of major wound complications following pelvic resection for bone sarcoma.
J Surg Oncol
; 130(2): 293-300, 2024 Aug.
Article
en En
| MEDLINE
| ID: mdl-38764259
ABSTRACT
BACKGROUND:
Given the paucity of data, the objective of this study is to evaluate the association between obesity and major wound complications following pelvic bone sarcoma surgery specifically.METHODS:
Patients who underwent pelvic resection for bone sarcoma from 2005 to 2021 with a minimum 6-month follow-up were reviewed. Patients with benign tumors, primary soft tissue sarcomas, local recurrence at presentation, pelvic metastatic disease, and underweight patients were excluded. A major wound complication was defined as the need for a secondary debridement procedure. Differences in baseline demographics, surgical factors, postoperative complications, and functional outcomes were compared between obese and nonobese patients. A multivariate logistic regression was performed to identify independent risk factors for major wound complications, and a Kaplan-Meier analysis to estimate overall survival between both groups.RESULTS:
Of the 93 included patients, 21 were obese (body mass index ≥ 30 kg/m2). The obesity group had a significantly higher rate of major wound complication (52% vs. 26%, p = 0.034) and a lower Toronto Extremity Salvage Score at 1-year postoperatively (47.5 vs. 71.4, p = 0.025). Obesity was the only independent risk factor in the multivariate analysis. No differences in overall survival were demonstrated between groups.CONCLUSIONS:
Obesity is a significant risk factor for major wound complications in pelvic bone sarcoma treatment. This highlights the importance of careful perioperative optimization and wound management.Palabras clave
Texto completo:
1
Base de datos:
MEDLINE
Asunto principal:
Huesos Pélvicos
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Complicaciones Posoperatorias
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Neoplasias Óseas
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Obesidad
Idioma:
En
Revista:
J Surg Oncol
Año:
2024
Tipo del documento:
Article