Arthropod promoters for genetic control of disease vectors.
Trends Parasitol
; 40(7): 619-632, 2024 Jul.
Article
en En
| MEDLINE
| ID: mdl-38824066
ABSTRACT
Vector-borne diseases (VBDs) impose devastating effects on human health and a heavy financial burden. Malaria, Lyme disease, and dengue fever are just a few examples of VBDs that cause severe illnesses. The current strategies to control VBDs consist mainly of environmental modification and chemical use, and to a small extent, genetic approaches. The genetic approaches, including transgenesis/genome modification and gene-drive technologies, provide the basis for developing new tools for VBD prevention by suppressing vector populations or reducing their capacity to transmit pathogens. The regulatory elements such as promoters are required for a robust sex-, tissue-, and stage-specific transgene expression. As discussed in this review, information on the regulatory elements is available for mosquito vectors but is scant for other vectors.
Palabras clave
Texto completo:
1
Base de datos:
MEDLINE
Asunto principal:
Regiones Promotoras Genéticas
/
Enfermedades Transmitidas por Vectores
Idioma:
En
Revista:
Trends Parasitol
Asunto de la revista:
PARASITOLOGIA
Año:
2024
Tipo del documento:
Article