Change in Healthy Lifestyle and Subsequent Risk of Cognitive Impairment Among Chinese Older Adults: A National Community-Based Cohort Study.
J Gerontol A Biol Sci Med Sci
; 79(8)2024 Aug 01.
Article
en En
| MEDLINE
| ID: mdl-38836313
ABSTRACT
BACKGROUND:
The association between change in lifestyle and cognitive impairment remains uncertain.OBJECTIVES:
To investigate the association of change in lifestyle with cognitive impairment.METHODS:
In this study, 4 938 participants aged 65 or older were involved from the Chinese Longitudinal Healthy Longevity Survey for years 2008-2018. A weighted healthy lifestyle score was derived from 4 lifestyle factors (smoking, alcohol consumption, physical activity, and diet). Multivariable Cox proportional hazards regression models were applied to investigate the associations between 3-year changes in healthy lifestyle (2008-2011) and cognitive impairment (2011-2018).RESULTS:
Researchers documented 833 new-onset of cognitive impairments more than 20 097 person-years of follow up. Compared with those in the persistently unhealthy group, those in the improved and persistently healthy groups had a lower risk of cognitive impairment, with the multivariate-adjusted hazard ratios (HRs) of 0.67 (95% confidence interval (CI) 0.55, 0.83) and 0.53 (95% CI 0.40, 0.71), respectively. Furthermore, a significant interaction was observed between change in lifestyle and sex (p-interactionâ =â .032); the HRs were 0.48 (95% CI, 0.34, 0.69) for the improved group and 0.41 (95% CI 0.26, 0.64) for persistently healthy group among male vs 0.81 (95% CI, 0.63, 1.04) and 0.64 (95% CI, 0.44, 0.92) among female, respectively.CONCLUSIONS:
This study suggests that improving or maintaining a healthy lifestyle can significantly mitigate the risk of cognitive impairment in Chinese older adults. Additionally, researcher's findings emphasize the significance of maintaining a healthy lifestyle and highlights the potential positive impact of improving previous unhealthy habits, especially for older women.Palabras clave
Texto completo:
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Base de datos:
MEDLINE
Asunto principal:
Disfunción Cognitiva
/
Estilo de Vida Saludable
País/Región como asunto:
Asia
Idioma:
En
Revista:
J Gerontol A Biol Sci Med Sci
Asunto de la revista:
GERIATRIA
Año:
2024
Tipo del documento:
Article