Curvature-induced clustering of cell adhesion proteins.
Phys Rev E
; 109(5-1): 054406, 2024 May.
Article
en En
| MEDLINE
| ID: mdl-38907394
ABSTRACT
Cell adhesion proteins typically form stable clusters that anchor the cell membrane to its environment. Several works have suggested that cell membrane protein clusters can emerge from a local feedback between the membrane curvature and the density of proteins. Here, we investigate the effect of such a curvature-sensing mechanism in the context of cell adhesion proteins. We show how clustering emerges in an intermediate range of adhesion and curvature-sensing strengths. We identify key differences with the tilt-induced gradient sensing mechanism we previously proposed (Lin et al., arXiv2307.03670).
Texto completo:
1
Base de datos:
MEDLINE
Asunto principal:
Adhesión Celular
/
Membrana Celular
Idioma:
En
Revista:
Phys Rev E
/
Phys. rev., E (Online)
/
Physical review. E (Online)
Año:
2024
Tipo del documento:
Article