Long-Term Impact of Deep Brain Stimulation in Parkinson's Disease: Does It Affect Rehabilitation Outcomes?
Medicina (Kaunas)
; 60(6)2024 Jun 01.
Article
en En
| MEDLINE
| ID: mdl-38929544
ABSTRACT
Background and Objectives:
Although the growing literature is now focusing on the long-term effects of Deep Brain Stimulation (DBS) in Parkinson's disease (PD), there is still a large gap of knowledge about its long-term implications in rehabilitation. Therefore, this study aimed at investigating the effects of rehabilitation in PD patients years after DBS implantation. Materials andMethods:
This retrospective case-control study analyzed records from Moriggia-Pelascini Hospital, Italy from September 2022 to January 2024. Data of PD patients (n = 47) with (DBS group, n = 22) and without (control group, n = 25) DBS were considered. All study participants underwent a daily rehabilitation program lasting four weeks, including warm-up, aerobic exercises, strength training, postural exercises, and proprioceptive activities. The outcomes assessed were the Unified Parkinson's Disease Rating Scale (UPDRS), Berg Balance Scale (BBS), Timed Up and Go (TUG), 6 Min Walk Test (6MWT), and Self-Assessment Parkinson Disease Scale (SPDDS).Results:
DBS group showed significant improvements in terms of all outcome measures after the rehabilitation intervention (UPDRS III -7.0 (-11.5 to -1.0); p = 0.001; UPDRS I II IV -12.0 (-19.0 to -4.5); p = 0.001; BBS 7.0 (3.8 to 10.3); p < 0.001; TUG (s) -2.8 (-5.7 to -1.1); p < 0.001; SPDDS -8 (-13.0 to -4.0); p < 0.001; 6MWT (m) 81 (37.3 to 132.3); p < 0.001). No differences were reported in the between-group analysis (p NS).Conclusions:
This study emphasizes positive rehabilitation effects on PD patients irrespective of DBS status. Further research is essential to elucidate long-term effects of DBS on rehabilitation outcomes of PD patients.Palabras clave
Texto completo:
1
Base de datos:
MEDLINE
Asunto principal:
Enfermedad de Parkinson
/
Estimulación Encefálica Profunda
País/Región como asunto:
Europa
Idioma:
En
Revista:
Medicina (Kaunas)
Asunto de la revista:
MEDICINA
Año:
2024
Tipo del documento:
Article