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Inflammatory Bowel Diseases and the Efficacy of Probiotics as Functional Foods.
Vitetta, Luis; Oldfield, Debbie; Sali, Avni.
Afiliación
  • Vitetta L; Faculty of Medicine and Health, The University of Sydney, Sydney, NSW 2006, Australia.
  • Oldfield D; Research Department, National Institute of Integrative Medicine, Hawthorn, VIC 3122, Australia.
  • Sali A; Research Department, National Institute of Integrative Medicine, Hawthorn, VIC 3122, Australia.
Front Biosci (Elite Ed) ; 16(2): 13, 2024 May 08.
Article en En | MEDLINE | ID: mdl-38939911
ABSTRACT
Adverse intestinal microbiome profiles described as a dysbiotic gut are a complicit etiological operative factor that can progress and maintain inflammatory sequelae in the intestines. The disruption of the gut microbiome that ensues with intestinal dysbiosis is, for example, posited by decreases in the alpha-diversity of the gut microbiome, which is characterized by significant reductions in the abundance of bacterial members from the Bacteroidetes and Firmicutes phyla. Proteobacteria have often been recognized as gut microbial signatures of disease. For example, this happens with observed increases in abundance of the phyla Proteobacteria and Gammaproteobacteria, such as the adherent-invasive Escherichia coli strain, which has been significantly linked with maintaining inflammatory bowel diseases. Research on the administration of probiotics, often identified as gut-functional foods, has demonstrated safety, tolerability, and efficacy issues in treating inflammatory bowel diseases (IBDs). In this narrative review, we explore the efficacy of probiotics in treating IBDs with bacterial strain- and dose-specific characteristics and the association with multi-strain administration.
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Texto completo: 1 Base de datos: MEDLINE Asunto principal: Enfermedades Inflamatorias del Intestino / Probióticos / Microbioma Gastrointestinal Idioma: En Revista: Front Biosci (Elite Ed) Asunto de la revista: BIOLOGIA Año: 2024 Tipo del documento: Article

Texto completo: 1 Base de datos: MEDLINE Asunto principal: Enfermedades Inflamatorias del Intestino / Probióticos / Microbioma Gastrointestinal Idioma: En Revista: Front Biosci (Elite Ed) Asunto de la revista: BIOLOGIA Año: 2024 Tipo del documento: Article