A three-year review of lung cancer patient characteristics in a tertiary hospital.
Ghana Med J
; 57(3): 167-174, 2023 Sep.
Article
en En
| MEDLINE
| ID: mdl-38957673
ABSTRACT
Objective:
The study sought to determine clinical characteristics and histologic subtypes of a cohort of lung cancer patients in a tertiary facility.Design:
Retrospective review of the medical records of histology-confirmed lung cancer cases at the respiratory clinic over a 3-year period.Setting:
Respiratory Clinic, Korle-Bu Teaching Hospital, Accra, Ghana.Participants:
All adult patients with histologically diagnosed lung cancer were enrolled. Main outcomemeasures:
Lung cancer histological types.Results:
The proportion of lung cancer cases was 12.4%. The majority were women (57.8%) and the mean age at diagnosis was 55.8±16.0 years. The patients were predominantly non-smokers (61%). Common symptoms were chronic cough and chest pain. More than two-thirds of the cases presented in clinical stages III and IV with the predominant histological subtype being adenocarcinoma in smokers and non-smokers. Genetic testing for epidermal growth factor receptor (EGFR) and Anaplastic Lymphoma kinase (ALK) mutations were largely absent.Conclusions:
The majority of lung cancer patients presented late with advanced disease. Adenocarcinoma was the predominant histological subtype in a predominantly non-smoking population, with an increased prevalence among women less than 60 years. This should encourage testing for genetic mutations to improve patient survival.Funding:
None declared.Palabras clave
Texto completo:
1
Base de datos:
MEDLINE
Asunto principal:
Fumar
/
Centros de Atención Terciaria
/
Neoplasias Pulmonares
País/Región como asunto:
Africa
Idioma:
En
Revista:
Ghana Med J
Año:
2023
Tipo del documento:
Article