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Perceptions and experiences of community pharmacists with off-label prescribing in the pediatric population.
Noga, Fabiola; Hoti, Ela; Ibrahimi, Eliana; Toma, Diana; Malaj, Ledjan.
Afiliación
  • Noga F; Department of Pharmacy, University of Medicine Tirana, Tiranë, AL 1005, Albania.
  • Hoti E; Department of Pharmacy, University of Medicine Tirana, Tiranë, AL 1005, Albania.
  • Ibrahimi E; Department of Biology, University of Tirana, Tiranë, AL 1001, Albania.
  • Toma D; Order of Pharmacists of Albania, Tiranë, AL 1007, Albania.
  • Malaj L; Department of Pharmacy, University of Medicine Tirana, Tiranë, AL 1005, Albania.
Int J Pharm Pract ; 2024 Jul 04.
Article en En | MEDLINE | ID: mdl-38965914
ABSTRACT

OBJECTIVES:

This study aimed to investigate and provide insight into the prevalence and patterns of off-label drug use in the pediatric population from the perspective of community pharmacists, addressing the existing data gap in a developing setting.

METHODS:

A questionnaire-based cross-sectional study was conducted on Albanian community pharmacists in June 2021. The online administered survey explored the participants' demographic details, perceptions, and experiences with off-label prescriptions in pediatric patients. The statistical analysis conducted on the survey data comprised the construction of frequency tables and the application of the chi-square test for independence. KEY

FINDINGS:

Three hundred and thirty-six community pharmacists nationwide completed the survey, out of which 186 (55.3%) were practiced in Tirana, the capital of Albania. Over 80% of surveyed pharmacists (n = 275) had encountered off-label drug prescriptions in pediatric patients, yet only 40% of participants reported dispensing medicines for off-label use. Community pharmacists reported that general pediatricians tended to prescribe off-label medications more frequently than pediatric subspecialists or general practitioners. It was found that off-label prescriptions were more frequently observed among children aged between 2 and 11 years. Antibiotics were the most reported medicines for off-label use in this study mentioned in almost all off-label categories.

CONCLUSIONS:

Prescribing medicines for unapproved uses for the treatment of pediatric patients is present in community settings in Albania. This indicates the need for further data collection and analysis to understand off-label practices in our country's pediatric population comprehensively.
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Texto completo: 1 Base de datos: MEDLINE Idioma: En Revista: Int J Pharm Pract Asunto de la revista: FARMACIA Año: 2024 Tipo del documento: Article

Texto completo: 1 Base de datos: MEDLINE Idioma: En Revista: Int J Pharm Pract Asunto de la revista: FARMACIA Año: 2024 Tipo del documento: Article