Modern views of nutritional support in patients undergoing allogeneic stem cell transplantation.
Clin Nutr ESPEN
; 63: 400-408, 2024 Oct.
Article
en En
| MEDLINE
| ID: mdl-38971406
ABSTRACT
Patients undergoing allogeneic stem cell transplant (HSCT) have a higher risk of developing malnutrition. The aetiology is multifactorial and complex the conditioning regimen causes damages to the gastrointestinal tract that can contribute to trigger graft-versus-host disease and/or infectious complications that adversely affect food intake and the gut absorption of nutrients in transplant recipients. Consequently, patients might develop weight loss and muscle wasting. There is mounting evidence that insufficient muscle mass increases the risk of toxicity to many chemotherapy drugs. Furthermore, the screening for malnutrition, assessment and intervention can vary among HSCT centers. Hereby, we report the main nutritional clinical issues in the field of HSCT and the main nutritional tools used in this setting. Future clinical trials investigating nutritional tools and dose-escalating studies based on pre-treatment body composition assessment may help having the potential to alter cancer treatment paradigms.
Palabras clave
Texto completo:
1
Base de datos:
MEDLINE
Asunto principal:
Trasplante Homólogo
/
Apoyo Nutricional
/
Trasplante de Células Madre Hematopoyéticas
/
Desnutrición
Idioma:
En
Revista:
Clin Nutr ESPEN
/
Clinical nutrition ESPEN
Año:
2024
Tipo del documento:
Article