Lipidomics Profiling of the Linoleic Acid Metabolites After Whole-Body Vibration in Humans.
Methods Mol Biol
; 2816: 241-252, 2024.
Article
en En
| MEDLINE
| ID: mdl-38977603
ABSTRACT
Bioactive lipids have been identified as dynamic signaling lipid mediators (LMs). These fats have the ability to activate responses and control bodily functions either directly or indirectly. Linoleic Acid (LA) and Alpha Linoleic Acid (ALA) are types of omega 3 fatty acids that possess inflammatory properties and promote resolution of inflammation either through their own actions or through their metabolites known as oxylipins. In this chapter, we provide an explanation of a method that combines chromatography with tandem mass spectroscopy (LC MS/MS) to identify and measure all the metabolites derived from LA and ALA. Additionally, we employed the described methodology to analyze human serum samples obtained before and after whole-body vibration exercise training. The results indicated an increase in some of the LA and ALA LMs that have beneficial effects in regulating the cardiovascular system.
Palabras clave
Texto completo:
1
Base de datos:
MEDLINE
Asunto principal:
Vibración
/
Ácido Linoleico
/
Espectrometría de Masas en Tándem
/
Lipidómica
Idioma:
En
Revista:
Methods Mol Biol
Asunto de la revista:
BIOLOGIA MOLECULAR
Año:
2024
Tipo del documento:
Article