Extracorporeal Membrane Oxygenation Before 34 Wks' Gestation: A Single-Center Experience.
J Surg Res
; 301: 302-307, 2024 Sep.
Article
en En
| MEDLINE
| ID: mdl-38996721
ABSTRACT
INTRODUCTION:
Traditionally, gestational age <34 wk and weight <2 kg are considered relative contraindications to extracorporeal membrane oxygenation (ECMO). There is a paucity of information that explains the outcomes in this unique population of premature neonates. The purpose of this study is to examine outcomes of patients who undergo ECMO at <34 wk at a single institution.METHODS:
A single-center retrospective review was performed for neonates managed with ECMO in the neonatal intensive care unit from January 2012 to April 2022. Characteristics and outcome data were collected. The primary outcome studied was survival at discharge. Secondary outcomes were intraventricular hemorrhage, ischemic brain injury, and thrombosis. Data were analyzed with descriptive statistics.RESULTS:
Following exclusion, 107 patients were included with eight having initiating ECMO at <34 wk. Three (38%) patients, who received ECMO at <34 wk, incurred intraventricular hemorrhages compared to 14 (14%) in the ≥34-wk cohort. Two (25%), who underwent ECMO at <34 wk, exhibited signs of brain ischemia on imaging compared to 9 (9%) in those ≥34 wk, and 3 (38%) patients <34 wk experienced thrombosis compared to 31 (31%) in the ≥34-wk cohort. Five (63%) of those in the <34-wk cohort survived to discharge, similar to 61 (61%) in the ≥34 wk cohort.CONCLUSIONS:
Our data suggest that EGA <34 wk may not be a contraindication for ECMO, with appropriate counseling of potential risks.Palabras clave
Texto completo:
1
Base de datos:
MEDLINE
Asunto principal:
Oxigenación por Membrana Extracorpórea
/
Edad Gestacional
Idioma:
En
Revista:
J Surg Res
Año:
2024
Tipo del documento:
Article