Currarino syndrome with immature teratoma: A case report with review of literature.
J Cancer Res Ther
; 20(3): 1088-1091, 2024 Apr 01.
Article
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| MEDLINE
| ID: mdl-39023623
ABSTRACT
ABSTRACT Currarino syndrome (CS) is a rare congenital syndrome characterized by a triad of anorectal malformation, sacral deformity, and presacral mass. In about 50% of cases, it is caused by HLXB9 gene mutation in chromosome 7q36. A 13-month-male child presented with presacral discharging sinus with a history of surgery for anorectal malformation and perineal fistula at the time of birth. On detailed investigation, the child revealed to have anal atresia, hemisacrum, and presacral mass. Histopathology of presacral mass showed features of immature teratoma. The presacral mass in CS is mostly an anterior myelomeningocele or presacral teratoma. The development of immature teratoma in presacral mass is very rare. The histopathological identification of immature component of teratoma in the presacral mass of CS is important for risk stratification and further management. Suspicion of CS should be raised in any child presenting with partial phenotype of the triad.
Texto completo:
1
Base de datos:
MEDLINE
Asunto principal:
Canal Anal
/
Recto
/
Sacro
/
Siringomielia
/
Teratoma
/
Anomalías del Sistema Digestivo
Idioma:
En
Revista:
J Cancer Res Ther
Asunto de la revista:
NEOPLASIAS
/
TERAPEUTICA
Año:
2024
Tipo del documento:
Article