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Unlocking the Potential: immune functions of oligodendrocyte precursor cells.
Haroon, Amr; Seerapu, Harsha; Fang, Li-Pao; Weß, Jakob Heinrich; Bai, Xianshu.
Afiliación
  • Haroon A; Molecular Physiology, Center for Integrative Physiology and Molecular Medicine (CIPMM), University of Saarland, Homburg, Germany.
  • Seerapu H; Molecular Physiology, Center for Integrative Physiology and Molecular Medicine (CIPMM), University of Saarland, Homburg, Germany.
  • Fang LP; Molecular Physiology, Center for Integrative Physiology and Molecular Medicine (CIPMM), University of Saarland, Homburg, Germany.
  • Weß JH; Center for Gender-specific Biology and Medicine (CGBM), University of Saarland, Homburg, Germany.
  • Bai X; Molecular Physiology, Center for Integrative Physiology and Molecular Medicine (CIPMM), University of Saarland, Homburg, Germany.
Front Immunol ; 15: 1425706, 2024.
Article en En | MEDLINE | ID: mdl-39044821
ABSTRACT
Oligodendrocyte precursor cells (OPCs) have long been regarded as progenitors of oligodendrocytes, yet recent advances have illuminated their multifaceted nature including their emerging immune functions. This review seeks to shed light on the immune functions exhibited by OPCs, spanning from phagocytosis to immune modulation and direct engagement with immune cells across various pathological scenarios. Comprehensive understanding of the immune functions of OPCs alongside their other roles will pave the way for targeted therapies in neurological disorders.
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Texto completo: 1 Base de datos: MEDLINE Asunto principal: Células Precursoras de Oligodendrocitos Idioma: En Revista: Front Immunol / Front. immunol / Frontiers in immunology Año: 2024 Tipo del documento: Article

Texto completo: 1 Base de datos: MEDLINE Asunto principal: Células Precursoras de Oligodendrocitos Idioma: En Revista: Front Immunol / Front. immunol / Frontiers in immunology Año: 2024 Tipo del documento: Article