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The Application of Organoids in the Study of Antiviral Innate Immunity.
Wu, Tong; Zheng, Chunfu; Zou, Xiaodong.
Afiliación
  • Wu T; Kobilka Institute of Innovative Drug Discovery, School of Medicine, The Chinese University of Hong Kong, Shenzhen, Guangdong, China.
  • Zheng C; Department of Microbiology, Immunology and Infectious Diseases, University of Calgary, Calgary, AB, Canada.
  • Zou X; Department of Gastroenterology, The Second Affiliated Hospital, School of Medicine, The Chinese University of Hong Kong, Shenzhen & Longgang District People's Hospital of Shenzhen, Shenzhen, China. zouxiaodong@cuhk.edu.cn.
Methods Mol Biol ; 2854: 199-212, 2025.
Article en En | MEDLINE | ID: mdl-39192131
ABSTRACT
Antiviral innate immunity plays a critical role in the defense against viral infections, yet its complex interactions with viruses have been challenging to study using traditional models. Organoids, three-dimensional (3D) tissue-like structures derived from stem cells, have emerged as powerful tools for modeling human tissues and studying the complex interactions between viruses and the host innate immune system. This chapter summarizes relevant applications of organoids in antiviral innate immunity studies and provides detailed information and experimental procedures for using organoids to study antiviral innate immunity.
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Texto completo: 1 Base de datos: MEDLINE Asunto principal: Virosis / Organoides / Inmunidad Innata Idioma: En Revista: Methods Mol Biol Asunto de la revista: BIOLOGIA MOLECULAR Año: 2025 Tipo del documento: Article

Texto completo: 1 Base de datos: MEDLINE Asunto principal: Virosis / Organoides / Inmunidad Innata Idioma: En Revista: Methods Mol Biol Asunto de la revista: BIOLOGIA MOLECULAR Año: 2025 Tipo del documento: Article