The use of positron emission tomography for early detection of recurrent head and neck squamous cell carcinoma in postradiotherapy patients.
Laryngoscope
; 105(2): 135-9, 1995 Feb.
Article
en En
| MEDLINE
| ID: mdl-8544591
ABSTRACT
Positron emission tomography (PET) has recently proved to be highly sensitive in detecting known extracranial head and neck squamous cell carcinomas when compared to computed tomography and magnetic resonance imaging (MRI). The ability of PET to detect early subclinical recurrent squamous cell malignancies in patients who received primary radiotherapy was evaluated. A new PET-MRI coregistration technique was used to determine precise anatomic tumor location, enabling directed biopsies to confirm the presence of malignancy, and to plan additional therapeutic strategies. Ten patients underwent PET evaluation with intravenous [18F]-fluorodeoxyglucose and received postradiotherapy MRI scans. In all cases, PET accurately detected the presence of recurrent disease despite negative or equivocal MRI scans and indeterminate clinical examinations. PET appears to be highly effective in detecting early recurrent head and neck squamous cell malignancies in postirradiated patients.
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Base de datos:
MEDLINE
Asunto principal:
Carcinoma de Células Escamosas
/
Tomografía Computarizada de Emisión
/
Neoplasias de Cabeza y Cuello
/
Recurrencia Local de Neoplasia
Tipo de estudio:
Diagnostic_studies
/
Screening_studies
Idioma:
En
Revista:
Laryngoscope
Asunto de la revista:
OTORRINOLARINGOLOGIA
Año:
1995
Tipo del documento:
Article