Leukemia developing after 131I treatment for thyroid cancer in a patient with Werner's syndrome: molecular and cytogenetic studies.
Intern Med
; 34(9): 863-7, 1995 Sep.
Article
en En
| MEDLINE
| ID: mdl-8580557
ABSTRACT
A 40-year-old female patient with Werner's syndrome (WS) suffering from thyroid cancer and myelodysplastic syndrome (MDS) is reported. She had been diagnosed as having WS complicated with thyroid cancer seven years previously. Total thyroidectomy and radioactive iodine (131I, 100 mCi/year) therapy for seven years had slowed the progression of thyroid cancer. She suffered a sudden onset of MDS at the age of 40 years. After six months she died from overt leukemia. We found an additional chromosome aberration of chromosome 10 in the progression of leukemia from MDS.
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Base de datos:
MEDLINE
Asunto principal:
Síndrome de Werner
/
Neoplasias de la Tiroides
/
Leucemia Inducida por Radiación
/
Adenocarcinoma Papilar
/
Neoplasias Primarias Secundarias
/
Radioisótopos de Yodo
Idioma:
En
Revista:
Intern Med
Asunto de la revista:
MEDICINA INTERNA
Año:
1995
Tipo del documento:
Article