Evaluation of a line probe assay kit for characterization of rpoB mutations in rifampin-resistant Mycobacterium tuberculosis isolates from New York City.
J Clin Microbiol
; 35(5): 1281-3, 1997 May.
Article
en En
| MEDLINE
| ID: mdl-9114427
A commercial line probe assay kit (Inno-LiPA Rif.TB) for rapid identification of mutations in the rpoB gene associated with rifampin resistance in Mycobacterium tuberculosis was evaluated with a collection of 51 rifampin-resistant strains. Nine distinct rpoB mutations were identified. Concordances with automated sequence results for five wild-type kit probes and four probes for specific mutations were 94.1 and 100%, respectively. Overall concordance of the line probe assay kit with phenotypic rifampin susceptibility testing results was 90.2%.
Texto completo:
1
Base de datos:
MEDLINE
Asunto principal:
Rifampin
/
Tuberculosis
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ARN Polimerasas Dirigidas por ADN
/
Farmacorresistencia Microbiana
/
Antibióticos Antituberculosos
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Mycobacterium tuberculosis
País/Región como asunto:
America do norte
Idioma:
En
Revista:
J Clin Microbiol
Año:
1997
Tipo del documento:
Article