CML blast crisis resulting in biliary obstruction following BMT.
Bone Marrow Transplant
; 19(8): 853-4, 1997 Apr.
Article
en En
| MEDLINE
| ID: mdl-9134182
ABSTRACT
Allogeneic BMT is the treatment of choice for various hematologic malignancies. Despite careful patient scrutiny, a large number of patients experience significant morbidity and mortality due to procedure-related toxicity. Hepatobiliary toxicity presenting as biliary cholestasis, due to the preparative regimen (ie venoocclusive disease), supportive pharmaceuticals, and/or GVHD have been implicated. We report a unique cause of cholestasis in a patient undergoing BMT for CML. The cholestasis was found to be secondary to relapsed leukemia, which resulted in a granulocytic sarcoma obstructing the biliary ductal system.
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Base de datos:
MEDLINE
Asunto principal:
Leucemia Mieloide de Fase Crónica
/
Crisis Blástica
/
Colestasis
/
Trasplante de Médula Ósea
Tipo de estudio:
Diagnostic_studies
/
Etiology_studies
Idioma:
En
Revista:
Bone Marrow Transplant
Asunto de la revista:
TRANSPLANTE
Año:
1997
Tipo del documento:
Article